Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK1 | Q13464 | 3/20 | 0.46 |
| ▸ | CDK8 | P49336 | 2/20 | 0.46 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.46 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.46 |
| ▸ | CSF1R | P07333 | 1/20 | 0.46 |
| ▸ | PRKACA | P17612 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.46 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.46 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.46 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.46 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.46 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | FLT1 | P17948 | 1/20 | 0.41 |
| ▸ | CDK9 | P50750 | 1/20 | 0.41 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.41 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11536510 | 1.00 | ROCK1 (0.46) | ROCK1CDK8CHEK1MAP4K4CSF1R | |
| SCHEMBL31624542 | 0.74 | PARP1 (0.42) | ROCK1CDK8CHEK1MAP4K4CSF1R | |
| SCHEMBL1368544 | 0.74 | PARP1 (0.42) | ROCK1CDK8CHEK1MAP4K4CSF1R | |
| SCHEMBL6260887 | 0.74 | ADORA3 (0.39) | ROCK1CDK8CHEK1MAP4K4CSF1R | |
| SCHEMBL16244139 | 0.74 | RPS6KA5 (0.47) | ROCK1CDK8CHEK1MAP4K4CSF1R | |
| SCHEMBL38660441 | 0.74 | ADORA3 (0.39) | ROCK1CDK8CHEK1MAP4K4CSF1R | |
| SCHEMBL8145613 | 0.74 | PRKCI (0.44) | ROCK1CDK8CHEK1MAP4K4CSF1R | |
| SCHEMBL1599283 | 0.74 | MAPT (0.38) | ROCK1CDK8CHEK1MAP4K4CSF1R | |
| SCHEMBL20767747 | 0.73 | CDK8 (0.36) | ROCK1CDK8CHEK1MAP4K4CSF1R | |
| SCHEMBL31732605 | 0.72 | MAPK8 (0.43) | SMN1; SMN2MAPK8ALDH1A1BRD4BRPF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 393 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021058761-A1 | FIRST AND SECOND ORGANIC SEMICONDUCTOR LAYER AND ORGANIC ELECTRONIC DEVICE COMPRISING THE SAME | NOVALED GMBH (DE) | 2021-04-01 | — | — | WO | claimed |
| WO-2007074491-A1 | HETEROTRICYCLIC AMIDE DERIVATIVES AS NEUROKININ-l (NKl) RECEPTOR LIGANDS | UNIVERSITA DEGLI STUDI DI SIENA (IT) | 2007-07-05 | — | — | WO | claimed |
| US-20030144263-A1 | Oxazolidinone derivatives, process for their preparation and pharmaceutical compositions containing them | SYNGENTA LIMITED (GB) | 2003-07-31 | — | — | US | claimed |
| US-4990602-A | Bactericides | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 1991-02-05 | — | — | US | claimed |
| EP-0233800-B1 | Imidazo[1,2-a]quinoline derivatives, their preparation and therapeutical use thereof | SYNTHELABO (FR) | 1990-02-28 | — | — | EP | claimed |
| US-4675323-A | SLEEP INDUCING HYPNOTIC, ANTIULCER ANDOR ANTICONVULSANT AGEN T, ANALGESICS | SYNTHELABO (FR) | 1987-06-23 | — | — | US | claimed |
| EP-0062580-B1 | IMIDAZO(1,2-A)QUINOLINE DERIVATIVES | ROUSSEL-UCLAF (FR) | 1985-11-06 | — | — | EP | claimed |
| US-4387098-A | Imidazo[1,2-a]quinoline derivatives useful as anxiolytics | ROUSSEL UCLAF (FR) | 1983-06-07 | — | — | US | claimed |
| US-12022728-B2 | Organic electroluminescent element and electronic device | IDEMITSU KOSAN CO., LTD. (JP) | 2024-06-25 | — | — | US | disclosed |
| US-20230242556-A1 | NOVEL METHOD FOR MANUFACTURING DEUTERATED BORON COMPOUND | SFC CO., LTD. (KR) | 2023-08-03 | — | — | US | disclosed |
| US-20230242556-A1 | NOVEL METHOD FOR MANUFACTURING DEUTERATED BORON COMPOUND | SFC CO., LTD. (KR) | 2023-08-03 | — | — | US | disclosed |
| US-11691983-B2 | Specifically substituted benzofuro- and benzothienoquinolines for organic light emitting diodes | IDEMITSU KOSAN CO., LTD. (JP) | 2023-07-04 | — | — | US | disclosed |
| US-11672172-B2 | Heterocyclic compound comprising aromatic amine group and organic light-emitting diode including the same | SFC CO., LTD. (KR) | 2023-06-06 | — | — | US | disclosed |
| US-11672172-B2 | Heterocyclic compound comprising aromatic amine group and organic light-emitting diode including the same | SFC CO., LTD. (KR) | 2023-06-06 | — | — | US | disclosed |
| US-4163745-A | ANTIDIABETIC, HYPOGLYCEMIC | PFIZER INC. (US) | 1979-08-07 | — | — | US | disclosed |
| US-4141898-A | Imidazo pyridinium quaternary salts as hypoglycemic agents | PFIZER INC. (US) | 1979-02-27 | — | — | US | disclosed |
| US-4093616-A | PYRROLO(1,2-A)PYRAZINIUM, PYRAZOLO(1,5-A)PYRIDINIUM, 1H-IMIDAZO(2,1-A)ISOQUINOLINIUM, OR IMIDAZO(5,1-A)ISOQUINOLINIUM SALTS | PFIZER INC. (US) | 1978-06-06 | — | — | US | disclosed |
| US-4075343-A | Anti-allergenic 5-alkoxyimidazo[1,2-A]quinoline-2-carboxylic acids and derivatives thereof | PFIZER INC. (US) | 1978-02-21 | — | — | US | disclosed |
| US-4061754-A | HYPOTENSIVE | JOHN WYETH & BROTHER LIMITED (EN) | 1977-12-06 | — | — | US | disclosed |
| US-4044015-A | Imidazopyridinium compounds as hypoglycemic agents | PFIZER INC. (US) | 1977-08-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030144263-A1 | Oxazolidinone derivatives, process for their preparation and pharmaceutical compositions containing them | CYP3A5, CYP2D6, OXA1L | ROCK1 3315/4885CDK8 1954/4885CHEK1 2016/4885 |
| US-11691983-B2 | Specifically substituted benzofuro- and benzothienoquinolines for organic light emitting diodes | KCNQ2, KCNQ1, KCNQ4 | ROCK1 4688/4885CDK8 3966/4885CHEK1 3653/4885 |
| US-20230242556-A1 | NOVEL METHOD FOR MANUFACTURING DEUTERATED BORON COMPOUND | BCL6B, BRD7, DBF4 | ROCK1 4239/4885CDK8 599/4885CHEK1 1417/4885 |
| US-12022728-B2 | Organic electroluminescent element and electronic device | L1CAM, ESR1, LEF1 | ROCK1 3101/4885CDK8 2204/4885CHEK1 3394/4885 |
| US-11672172-B2 | Heterocyclic compound comprising aromatic amine group and organic light-emitting diode including the same | DDC, TYR, AOC2 | ROCK1 4165/4885CDK8 646/4885CHEK1 1545/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.