SCHEMBL31565733

SCHEMBL31565733

O=C(Cl)C1C(c2cc(Cl)c(Cl)c(C(F)(F)F)c2)C1(Cl)Cl

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
NOTUM Q6P988 1/20 0.31
KDR P35968 1/20 0.31
EPHX2 P34913 1/20 0.30
CCR2 P41597 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29425661 0.89 NOTUM (0.32) NOTUMKDRCCR2
SCHEMBL20051063 0.89 NOTUM (0.32) NOTUMKDRCCR2
SCHEMBL23465601 0.89 NOTUM (0.32) NOTUMKDRCCR2
SCHEMBL30739637 0.87 SLC9A1 (0.33) NOTUMKDR
SCHEMBL29243271 0.85 MEN1 (0.33)
SCHEMBL20076411 0.82 NOTUM (0.31) NOTUM
SCHEMBL31565732 0.81 MEN1 (0.34)
SCHEMBL31549989 0.79 MEN1 (0.36)
SCHEMBL29493871 0.77 CES2 (0.40) CCR2
SCHEMBL20051061 0.77 NOTUM (0.35) NOTUM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119954677-A Cyclopropionamide substituted benzamide derivative and preparation method and application thereof 山东省联合农药工业有限公司 2025-05-09 CN disclosed