Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | KMO | O15229 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3265872 | 0.88 | CYP3A4 (0.38) | TSHRHTTALDH1A1POLBCYP1A2 | |
| SCHEMBL4143883 | 0.73 | TSHR (0.50) | TSHRHTTKMOALDH1A1POLB | |
| SCHEMBL4757223 | 0.71 | ATAD2 (0.32) | TSHRHTTPOLBGAA | |
| SCHEMBL6362069 | 0.70 | — | — | |
| SCHEMBL24992343 | 0.70 | KMO (0.52) | TSHRHTTKMOALDH1A1POLB | |
| SCHEMBL6554603 | 0.70 | L3MBTL1 (0.39) | ALDH1A1POLBCYP1A2CYP2C9MAPT | |
| SCHEMBL4553513 | 0.69 | CYP3A4 (0.41) | TSHRALDH1A1POLBCYP1A2CYP2C9 | |
| SCHEMBL13803831 | 0.68 | HTT (0.39) | TSHRHTTKMOALDH1A1POLB | |
| Propionic Acid SCHEMBL29774514 | 0.68 | — | — | |
| SCHEMBL17213429 | 0.67 | HTT (0.36) | TSHRHTTALDH1A1POLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118063689-B | Polymer-drug conjugate for fibroblast activation protein-alpha response to hydrolysis charge inversion, and preparation method and application thereof | 锐康九域(厦门)医药科技有限公司 | 2025-01-28 | — | — | CN | disclosed |
| CN-118063689-A | Polymer-drug conjugate for fibroblast activation protein-alpha response to hydrolysis charge inversion, and preparation method and application thereof | 锐康九域(厦门)医药科技有限公司 | 2024-05-24 | — | — | CN | disclosed |