SCHEMBL3265872

SCHEMBL3265872

C=CCN1C(=O)COC1=O

nearest known ligand 0.39

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.38
POLB P06746 3/20 0.36
LMNA P02545 1/20 0.36
ALDH1A1 P00352 2/20 0.34
CASP3 P42574 1/20 0.34
CYP1A2 P05177 1/20 0.34
CYP2C9 P11712 1/20 0.34
L3MBTL1 Q9Y468 2/20 0.33
MAPT P10636 2/20 0.33
TSHR P16473 3/20 0.33
MAPK1 P28482 1/20 0.33
KDM4E B2RXH2 1/20 0.33
RXFP1 Q9HBX9 1/20 0.32
ATAD2 Q6PL18 1/20 0.31
CECR2 Q9BXF3 1/20 0.31
GAA P10253 1/20 0.30
HTT P42858 1/20 0.30
CNR1 P21554 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Propionic Acid SCHEMBL29243304 0.88 TSHR (0.37) CYP3A4POLBLMNAALDH1A1CYP1A2
SCHEMBL4757223 0.81 ATAD2 (0.32) POLBTSHRATAD2CECR2GAA
SCHEMBL6554603 0.80 L3MBTL1 (0.39) CYP3A4POLBLMNAALDH1A1CASP3
SCHEMBL4553513 0.78 CYP3A4 (0.41) CYP3A4POLBLMNAALDH1A1CASP3
SCHEMBL11779672 0.73
SCHEMBL2460358 0.72 KMT2A (0.33) POLBALDH1A1TSHRKDM4EATAD2
SCHEMBL474524 0.72 TSHR (0.56) POLBLMNAALDH1A1CYP2C9L3MBTL1
SCHEMBL6362069 0.71
SCHEMBL4143883 0.71 TSHR (0.50) POLBALDH1A1L3MBTL1TSHRATAD2
SCHEMBL16116448 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7645798-B2 N-(2-hydroxyalkanoyl)-N,N′-dialkylureas and a process for their preparation CHORISIS S.R.L. (IT) 2010-01-12 US claimed
EP-1893668-B1 N-(2-HYDROXYALKANOYL) -N,N'-DIALKYLUREAS AND A PROCESS FOR THEIR PREPARATION CHORISIS S R L (IT) 2009-07-29 EP claimed
US-20080085937-A1 N-(2-Hydroxyalkanoyl)-N,N'-Dialkylureas and a process for their preparation CHORISIS S.R.L. (IT) 2008-04-10 US claimed
EP-1893668-A1 N-(2-HYDROXYALKANOYL) -N,N'-DIALKYLUREAS AND A PROCESS FOR THEIR PREPARATION Chorisis S.R.L. (IT) 2008-03-05 EP claimed
WO-2006122782-A1 N-(2-HYDROXYALKANOYL) -N,N'-DIALKYLUREAS AND A PROCESS FOR THEIR PREPARATION CHORISIS S.R.L. (IT) 2006-11-23 WO claimed
EP-0652262-B1 Reactive dyestuffs, their preparation and use BAYER AG (DE) 2000-07-12 EP claimed
US-6025478-A HIGH REACTIVITY AND FIXING CAPACITY, GOOD LOW TEMPERATURE DYEING, GOOD COLOR INTENSITY, LIGHTFASTNESS, WASHFASTNESS BAYER AG (DE) 2000-02-15 US claimed
EP-0652262-A1 Reactive dyestuffs, their preparation and use BAYER AG (DE) 1995-05-10 EP claimed
JP-3215477-A None JP disclosed
WO-2023122956-A1 ELECTROLYTE, ELECTROCHEMICAL APPARATUS CONTAINING SAME AND ELECTRONIC APPARATUS 宁德新能源科技有限公司 2023-07-06 WO disclosed
US-7645798-B2 N-(2-hydroxyalkanoyl)-N,N′-dialkylureas and a process for their preparation CHORISIS S.R.L. (IT) 2010-01-12 US disclosed
EP-1893668-B1 N-(2-HYDROXYALKANOYL) -N,N'-DIALKYLUREAS AND A PROCESS FOR THEIR PREPARATION CHORISIS S R L (IT) 2009-07-29 EP disclosed
US-20080085937-A1 N-(2-Hydroxyalkanoyl)-N,N'-Dialkylureas and a process for their preparation CHORISIS S.R.L. (IT) 2008-04-10 US disclosed
EP-1893668-A1 N-(2-HYDROXYALKANOYL) -N,N'-DIALKYLUREAS AND A PROCESS FOR THEIR PREPARATION Chorisis S.R.L. (IT) 2008-03-05 EP disclosed
WO-2006122782-A1 N-(2-HYDROXYALKANOYL) -N,N'-DIALKYLUREAS AND A PROCESS FOR THEIR PREPARATION CHORISIS S.R.L. (IT) 2006-11-23 WO disclosed
US-6376656-B1 DISAZO DYES, TRIAZINE DYES DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 2002-04-23 US disclosed
EP-0652262-B1 Reactive dyestuffs, their preparation and use BAYER AG (DE) 2000-07-12 EP disclosed
US-6025478-A HIGH REACTIVITY AND FIXING CAPACITY, GOOD LOW TEMPERATURE DYEING, GOOD COLOR INTENSITY, LIGHTFASTNESS, WASHFASTNESS BAYER AG (DE) 2000-02-15 US disclosed
EP-0652262-A1 Reactive dyestuffs, their preparation and use BAYER AG (DE) 1995-05-10 EP disclosed
JP-H03215477-A COMPOUND HAVING ASYMMETRIC CARBON ATOM AND NONLINEAR OPTICAL MATERIAL COMPOSED THEREOF FUJI PHOTO FILM CO LTD 1991-09-20 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080085937-A1 N-(2-Hydroxyalkanoyl)-N,N'-Dialkylureas and a process for their preparation ADRA1A, CYP8B1, CNR1 CYP3A4 1117/4885POLB 1447/4885LMNA 831/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.