Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR4 | P51679 | 10/20 | 0.39 |
| ▸ | SIRT6 | Q8N6T7 | 2/20 | 0.37 |
| ▸ | CD274 | Q9NZQ7 | 3/20 | 0.36 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | NNMT | P40261 | 1/20 | 0.33 |
| ▸ | EDNRA | P25101 | 1/20 | 0.33 |
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.32 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7544018 | 0.75 | POLB (0.38) | CCR4SIRT6CD274PDCD1POLB | |
| SCHEMBL7544495 | 0.74 | CDC7 (0.39) | SIRT6POLBNNMT | |
| SCHEMBL14780231 | 0.72 | MEN1 (0.44) | CCR4SIRT6POLBEDNRA | |
| SCHEMBL31214143 | 0.71 | NPSR1 (0.45) | CCR4EDNRA | |
| SCHEMBL11726239 | 0.71 | NPSR1 (0.45) | CCR4 | |
| SCHEMBL1731368 | 0.71 | CCR4 (0.38) | CCR4CD274PDCD1MAPKAPK2 | |
| SCHEMBL1732310 | 0.71 | CCR4 (0.41) | CCR4CD274PDCD1MAPKAPK2 | |
| SCHEMBL23093183 | 0.70 | CCR4 (0.40) | CCR4CD274PDCD1EDNRAPDCD1LG2 | |
| SCHEMBL6170483 | 0.70 | CCR4 (0.43) | CCR4CD274PDCD1EDNRA | |
| SCHEMBL29212506 | 0.70 | NNMT (0.37) | SIRT6POLBNNMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117794529-A | POLO-like kinase 4 inhibitors | 欧瑞克制药公司 | 2024-03-29 | — | — | CN | disclosed |