Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | COXFA4 | O00483 | 1/20 | 0.45 |
| ▸ | ABCC9 | O60706 | 8/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.37 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30874710 | 1.00 | COXFA4 (0.45) | COXFA4ABCC9PTPN1HIF1AEPAS1 | |
| SCHEMBL29244241 | 0.86 | COXFA4 (0.48) | COXFA4PTPN1HIF1AEPAS1ALDH1A1 | |
| SCHEMBL30874666 | 0.86 | COXFA4 (0.48) | COXFA4PTPN1HIF1AEPAS1ALDH1A1 | |
| SCHEMBL30874687 | 0.85 | COXFA4 (0.47) | COXFA4PTPN1HIF1AEPAS1ALDH1A1 | |
| SCHEMBL29244242 | 0.85 | ALDH1A1 (0.49) | COXFA4PTPN1HIF1AEPAS1ALDH1A1 | |
| SCHEMBL30874665 | 0.85 | ALDH1A1 (0.49) | COXFA4PTPN1HIF1AEPAS1ALDH1A1 | |
| SCHEMBL29244240 | 0.85 | COXFA4 (0.47) | COXFA4PTPN1HIF1AEPAS1ALDH1A1 | |
| SCHEMBL29244237 | 0.85 | COXFA4 (0.49) | COXFA4PTPN1HIF1AEPAS1ALDH1A1 | |
| SCHEMBL29244235 | 0.83 | COXFA4 (0.53) | COXFA4HIF1AEPAS1ALDH1A1HPGD | |
| SCHEMBL30874650 | 0.83 | COXFA4 (0.53) | COXFA4HIF1AEPAS1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117946055-A | Chromene aryl hydrazide derivative and preparation method and application thereof | 贵州医科大学 | 2024-04-30 | — | — | CN | disclosed |