Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 3/20 | 0.43 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.43 |
| ▸ | GRM5 | P41594 | 3/20 | 0.43 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.43 |
| ▸ | GBA1 | P04062 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MMP1 | P03956 | 3/20 | 0.40 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | METAP1 | P53582 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1229628 | 0.80 | LOXL2 (0.50) | SMN1; SMN2HTTMMP13ADAMTS4LOXL2 | |
| SCHEMBL8061919 | 0.79 | VDR (0.47) | SMN1; SMN2HTTKEAP1NFE2L2CYP1A2 | |
| SCHEMBL12472263 | 0.78 | HTT (0.56) | SMN1; SMN2HTTKEAP1NFE2L2GRM5 | |
| SCHEMBL22502398 | 0.75 | L3MBTL1 (0.51) | HTT | |
| SCHEMBL29378984 | 0.75 | L3MBTL1 (0.51) | HTT | |
| SCHEMBL5870619 | 0.75 | MEN1 (0.54) | SMN1; SMN2HTTKEAP1NFE2L2ADAM17 | |
| SCHEMBL13954243 | 0.75 | VDR (0.51) | SMN1; SMN2HTTKEAP1NFE2L2TP53 | |
| SCHEMBL7658394 | 0.75 | MMP1 (0.41) | KEAP1NFE2L2MMP13GRM5MMP1 | |
| SCHEMBL3777059 | 0.74 | SYK (0.50) | SMN1; SMN2MAPT | |
| SCHEMBL29995677 | 0.74 | SYK (0.50) | SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118239926-A | TLR7 and 8 inhibitors, preparation method and application thereof | 上海深势唯思科技有限责任公司 | 2024-06-25 | — | — | CN | disclosed |