Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPO | P22079 | 3/20 | 0.51 |
| ▸ | TP53 | P04637 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | TPH1 | P17752 | 1/20 | 0.49 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.47 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.47 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.46 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30910333 | 1.00 | LPO (0.51) | LPOTP53MAPTLMNATPH1 | |
| SCHEMBL29246485 | 0.89 | ABL1 (0.47) | LPOMAPTLMNATPH1FGFR1 | |
| SCHEMBL5460397 | 0.86 | ABL1 (0.57) | TP53MAPTLMNATPH1FGFR1 | |
| Bicarbonate SCHEMBL28413960 | 0.83 | TPH1 (0.67) | TP53MAPTLMNATPH1FGFR1 | |
| SCHEMBL17507859 | 0.81 | FGFR1 (0.49) | MAPTLMNATPH1FGFR1FGFR4 | |
| SCHEMBL3541053 | 0.81 | NOTUM (0.58) | FGFR1FGFR4MEN1KMT2A | |
| SCHEMBL31632948 | 0.81 | FGFR1 (0.53) | MAPTSLC2A1FGFR1FGFR4THRB | |
| SCHEMBL3393621 | 0.81 | SLC2A1 (0.58) | LPOTP53MAPTLMNATPH1 | |
| SCHEMBL5458724 | 0.81 | YTHDC1 (0.61) | TP53YTHDC1FGFR1FGFR4RXFP1 | |
| SCHEMBL19599016 | 0.77 | FGFR1 (0.48) | TP53TPH1FGFR1FGFR4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117865965-B | Pyrrolopyrimidine-4-amine and pyrazolopyrimidine-4-amine derivatives, preparation method and application thereof | 贵州省天然产物研究中心 | 2024-06-28 | — | — | CN | disclosed |