Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.57 |
| ▸ | BCR | P11274 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | BMPR1B | O00238 | 3/20 | 0.48 |
| ▸ | ACVR1B | P36896 | 3/20 | 0.48 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.48 |
| ▸ | ACVRL1 | P37023 | 3/20 | 0.48 |
| ▸ | ACVR1 | Q04771 | 3/20 | 0.48 |
| ▸ | BMPR1A | P36894 | 1/20 | 0.48 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.47 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TPH1 | P17752 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29246485 | 0.89 | ABL1 (0.47) | ABL1BCRLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL29246271 | 0.86 | LPO (0.51) | ABL1BCRLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL30910333 | 0.86 | LPO (0.51) | ABL1BCRLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL9046752 | 0.85 | ABL1 (0.56) | ABL1BCRLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL17507859 | 0.84 | FGFR1 (0.49) | ABL1BCRLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL30910334 | 0.84 | FGFR1 (0.55) | ABL1BCRLMNASMN1; SMN2FGFR1 | |
| SCHEMBL29246277 | 0.84 | FGFR1 (0.55) | ABL1BCRLMNASMN1; SMN2FGFR1 | |
| SCHEMBL30910343 | 0.81 | FGFR1 (0.56) | ABL1BCRFGFR1FGFR4MAPT | |
| SCHEMBL29246282 | 0.81 | FGFR1 (0.56) | ABL1BCRFGFR1FGFR4MAPT | |
| SCHEMBL3541053 | 0.81 | NOTUM (0.58) | FGFR1FGFR4NOTUMKCNH2SCN5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117865965-B | Pyrrolopyrimidine-4-amine and pyrazolopyrimidine-4-amine derivatives, preparation method and application thereof | 贵州省天然产物研究中心 | 2024-06-28 | — | — | CN | disclosed |
| US-20070203159-A1 | Purine compounds | UNIVERSITETET I OLSO (NO) | 2007-08-30 | — | — | US | disclosed |
| US-20070203159-A1 | Purine compounds | UNIVERSITETET I OLSO (NO) | 2007-08-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070203159-A1 | Purine compounds | PNP, UMPS, TYMP | ABL1 559/4885BCR 1842/4885LMNA 2001/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.