Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NNMT | P40261 | 14/20 | 0.41 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.36 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29247562 | 1.00 | NNMT (0.41) | NNMTSLC22A12KDM1AACACBPRMT5 | |
| SCHEMBL29247145 | 0.89 | SLC22A12 (0.39) | NNMTSLC22A12ACACBPRMT5WDR77 | |
| SCHEMBL30372589 | 0.89 | SLC22A12 (0.39) | NNMTSLC22A12ACACBPRMT5WDR77 | |
| SCHEMBL29247142 | 0.89 | SLC22A12 (0.39) | NNMTSLC22A12ACACBPRMT5WDR77 | |
| SCHEMBL30974881 | 0.83 | GPR119 (0.38) | NNMTSLC22A12ACACBPRMT5WDR77 | |
| SCHEMBL29247169 | 0.83 | GPR119 (0.38) | NNMTSLC22A12ACACBPRMT5WDR77 | |
| SCHEMBL29247166 | 0.83 | GPR119 (0.38) | NNMTSLC22A12ACACBPRMT5WDR77 | |
| SCHEMBL24753099 | 0.82 | PIP4K2A (0.44) | SLC22A12ACACBPRMT5WDR77 | |
| SCHEMBL21130022 | 0.82 | SLC22A12 (0.40) | NNMTSLC22A12ACACBPRMT5WDR77 | |
| SCHEMBL30974787 | 0.82 | PRMT5 (0.41) | NNMTSLC22A12ACACBPRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4408850-A1 | MODULATORS OF TRPML, THEIR COMPOSITIONS AND METHODS OF USE | Caraway Therapeutics, Inc. (US) | 2024-08-07 | — | — | EP | disclosed |
| WO-2023055920-A1 | MODULATORS OF TRPML, THEIR COMPOSITIONS AND METHODS OF USE | CARAWAY THERAPEUTICS, INC. (US) | 2023-04-06 | — | — | WO | disclosed |