SCHEMBL29249779

SCHEMBL29249779

Cc1ccccc1S(=O)(=O)N1CCc2ccc(I)cc21

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.50
KMT2A Q03164 3/20 0.50
DRD3 P35462 5/20 0.47
HTR6 P50406 5/20 0.47
DRD2 P14416 3/20 0.47
HTR1A P08908 1/20 0.47
HTR1D P28221 1/20 0.47
HTR1B P28222 1/20 0.47
HTR2C P28335 1/20 0.47
HTR7 P34969 1/20 0.47
ADRA1B P35368 1/20 0.47
HTR2B P41595 1/20 0.47
HTR4 Q13639 1/20 0.47
RAB9A P51151 2/20 0.47
TSHR P16473 2/20 0.45
L3MBTL1 Q9Y468 2/20 0.45
CRHBP P24387 1/20 0.44
CRHR2 Q13324 1/20 0.44
ALDH1A1 P00352 3/20 0.43
SMN1; SMN2 Q16637 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29249701 0.84 MEN1 (0.52) MEN1KMT2ADRD3HTR6DRD2
SCHEMBL2696317 0.83 MEN1 (0.65) MEN1KMT2ARAB9ATSHRL3MBTL1
SCHEMBL17064153 0.78 HTR6 (0.57) MEN1KMT2ADRD3HTR6DRD2
SCHEMBL4869072 0.74 CRHBP (0.62) MEN1KMT2ATSHRL3MBTL1CRHBP
SCHEMBL4865019 0.72 KMT2A (0.51) MEN1KMT2ARAB9ATSHRL3MBTL1
SCHEMBL29100371 0.71 KMT2A (0.44) MEN1KMT2AHTR2CRAB9ATSHR
SCHEMBL17065538 0.71 MEN1 (0.60) MEN1KMT2ARAB9ATSHRL3MBTL1
SCHEMBL2695301 0.70 PKM (0.69) MEN1KMT2ARAB9ATSHRL3MBTL1
SCHEMBL4863822 0.70 L3MBTL1 (0.53) MEN1KMT2ATSHRL3MBTL1CRHBP
SCHEMBL16061976 0.69 MAPT (0.60) MEN1KMT2AHTR6RAB9ATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112094259-B Iodine (III) -mediated radiofluorination 通用医疗公司 2023-09-01 CN disclosed