Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 4/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | OGG1 | O15527 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.34 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30425275 | 1.00 | MAPK1 (0.40) | MAPK1MCL1OGG1LMNAPDE10A | |
| SCHEMBL2967033 | 0.79 | MAPK1 (0.38) | MAPK1MCL1OGG1LMNAPDE10A | |
| SCHEMBL3820047 | 0.76 | ALDH1A1 (0.48) | MAPK1MCL1OGG1LMNAPDE10A | |
| SCHEMBL2977917 | 0.76 | ALDH1A1 (0.35) | LMNAMAPTKDM4EALDH1A1EPAS1 | |
| SCHEMBL4128387 | 0.72 | MAPK1 (0.33) | MAPK1MCL1OGG1LMNAPDE10A | |
| SCHEMBL4380910 | 0.71 | MAPK1 (0.43) | MAPK1MCL1OGG1HDAC3HDAC4 | |
| SCHEMBL350288 | 0.69 | POLB (0.39) | MAPK1MCL1OGG1LMNAHDAC3 | |
| SCHEMBL10167535 | 0.68 | MMP3 (0.32) | MAPK1MCL1LMNAPDE10AMAPT | |
| SCHEMBL11095814 | 0.68 | ALDH1A1 (0.39) | MAPK1MCL1OGG1LMNAMAPT | |
| SCHEMBL13615128 | 0.68 | TYK2 (0.47) | MAPK1MCL1OGG1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116323566-B | Sulfanone compound and preparation method and medical application thereof | 中国医药研究开发中心有限公司 | 2024-05-17 | — | — | CN | disclosed |