Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | OGG1 | O15527 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30425275 | 0.79 | MAPK1 (0.40) | MAPK1MCL1LMNAPDE10AMAPT | |
| SCHEMBL3820047 | 0.79 | ALDH1A1 (0.48) | MAPK1MCL1LMNAPDE10AMAPT | |
| SCHEMBL29250366 | 0.79 | MAPK1 (0.40) | MAPK1MCL1LMNAPDE10AMAPT | |
| SCHEMBL1710781 | 0.79 | SMN1; SMN2 (0.35) | MAPK1LMNAMAPTALDH1A1GAA | |
| SCHEMBL4128387 | 0.75 | MAPK1 (0.33) | MAPK1MCL1LMNAPDE10AMAPT | |
| SCHEMBL4380910 | 0.70 | MAPK1 (0.43) | MAPK1MCL1MAPTALDH1A1MEN1 | |
| SCHEMBL13903676 | 0.70 | PRKCI (0.35) | MAPK1MCL1LMNAMAPTALDH1A1 | |
| SCHEMBL13903778 | 0.70 | GLP1R (0.33) | MAPK1MCL1LMNAMAPTALDH1A1 | |
| SCHEMBL2974515 | 0.69 | TAAR1 (0.34) | LMNAPDE10AOGG1 | |
| SCHEMBL4139724 | 0.69 | CRHR1 (0.40) | MAPK1LMNAMAPTALDH1A1OGG1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7776847-B2 | Benzisothiazoles useful for treating or preventing HCV infection | RIGEL PHARMACEUTICALS, INC. (US) | 2010-08-17 | — | — | US | disclosed |
| US-7776847-B2 | Benzisothiazoles useful for treating or preventing HCV infection | RIGEL PHARMACEUTICALS, INC. (US) | 2010-08-17 | — | — | US | disclosed |
| US-7776847-B2 | Benzisothiazoles useful for treating or preventing HCV infection | RIGEL PHARMACEUTICALS, INC. (US) | 2010-08-17 | — | — | US | disclosed |
| EP-1954138-A2 | INSECTICIDAL METHODS USING 3-AMINO-1,2-BENZISOTHIAZOLE DERIVATIVES | BASF SE (DE) | 2008-08-13 | — | — | EP | disclosed |
| EP-1853573-A1 | BENZISOTHIAZOLES USEFUL FOR TREATING OR PREVENTING HCV INFECTION | Rigel Pharmaceuticals, Inc. (US) | 2007-11-14 | — | — | EP | disclosed |
| WO-2007057407-A2 | INSECTICIDAL METHODS USING 3-AMINO-1,2-BENZISOTHIAZOLE DERIVATIVES | BASF SE (DE) | 2007-05-24 | — | — | WO | disclosed |
| US-20060229294-A1 | Benzisothiazoles useful for treating or preventing HCV infection | RIGEL PHARMACEUTICALS, INC. (US) | 2006-10-12 | — | — | US | disclosed |
| WO-2006091858-A1 | BENZISOTHIAZOLES USEFUL FOR TREATING OR PREVENTING HCV INFECTION | RIGEL PHARMACEUTICALS, INC. (US) | 2006-08-31 | — | — | WO | disclosed |
| US-4789747-A | BROAD LEAF PLANTS, GRASSES, WEEDS | BASF AKTIENGESELLSCHAFT (DE) | 1988-12-06 | — | — | US | disclosed |
| US-4761175-A | M-anilido-urethanes and herbicides containing these compounds | BASF AKTIENGESELLSCHAFT (DE) | 1988-08-02 | — | — | US | disclosed |
| EP-0037925-A1 | Substituted pyridazinones, process for their preparation, herbicides containing them and their use as herbicides | BASF Aktiengesellschaft (DE) | 1981-10-21 | — | — | EP | disclosed |
| EP-0035712-A1 | N-aryl(thiol) carbamates, process for their preparation and their use in combating undesired plant growth | BASF Aktiengesellschaft (DE) | 1981-09-16 | — | — | EP | disclosed |
| EP-0032242-A1 | 4H-3,1-benzoxazine derivatives, process for their preparation and their use in inhibiting the growth of unwanted plants | BASF Aktiengesellschaft (DE) | 1981-07-22 | — | — | EP | disclosed |
| EP-0028355-A1 | 1,2-Oxazolylalkyl carbamates, their preparation, their use as herbicides, and herbicides | BASF Aktiengesellschaft (DE) | 1981-05-13 | — | — | EP | disclosed |
| EP-0027915-A1 | Herbicidal agents based on diphenyl ethers and benzothiadiazinone dioxides or pyridinothiadiazinone dioxides, and their use | BASF Aktiengesellschaft (DE) | 1981-05-06 | — | — | EP | disclosed |
| EP-0025113-A1 | 5,6-Dihydro-1,2,4,6-thiatriazin(5)on-1.1-dioxides, process for their preparation and herbicides containing them | BASF Aktiengesellschaft (DE) | 1981-03-18 | — | — | EP | disclosed |
| EP-0024570-A1 | 5-Imino-imidazoline-2-ones, herbicides containing them and process for destructing undesired plants | BASF Aktiengesellschaft (DE) | 1981-03-11 | — | — | EP | disclosed |
| EP-0024669-A1 | Substituted N-benzoylanthranilic acid derivatives and their anhydro derivatives, process for their preparation, their use as herbicides and compositions therefor | BASF Aktiengesellschaft (DE) | 1981-03-11 | — | — | EP | disclosed |
| EP-0021324-A1 | m-Anilido urethanes and herbicidal compositions which contain them | BASF Aktiengesellschaft (DE) | 1981-01-07 | — | — | EP | disclosed |
| EP-0019760-A1 | Esters of 3-aryl-5-methyl-pyrazole-4-carboxylic acid, herbicides containing them, process for their preparation and their use | BASF Aktiengesellschaft (DE) | 1980-12-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060229294-A1 | Benzisothiazoles useful for treating or preventing HCV infection | HAVCR2, ZC3HAV1, MAVS | MAPK1 1959/4885MCL1 1082/4885LMNA 4468/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.