Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 8/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | REN | P00797 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.34 |
| ▸ | GLA | P06280 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | CASP1 | P29466 | 2/20 | 0.34 |
| ▸ | CASP7 | P55210 | 2/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3465045 | 1.00 | ALDH1A1 (0.36) | ALDH1A1KMT2AHPGDSMN1; SMN2L3MBTL1 | |
| SCHEMBL3465047 | 1.00 | ALDH1A1 (0.36) | ALDH1A1KMT2AHPGDSMN1; SMN2L3MBTL1 | |
| SCHEMBL2920516 | 0.91 | REN (0.36) | ALDH1A1KMT2ASMN1; SMN2RENGAA | |
| SCHEMBL14272005 | 0.91 | REN (0.36) | ALDH1A1KMT2ASMN1; SMN2RENRAB9A | |
| SCHEMBL3561065 | 0.91 | REN (0.36) | ALDH1A1KMT2ASMN1; SMN2RENRAB9A | |
| SCHEMBL2925320 | 0.91 | REN (0.36) | ALDH1A1KMT2ASMN1; SMN2RENRAB9A | |
| SCHEMBL1040158 | 0.89 | REN (0.36) | ALDH1A1KMT2ASMN1; SMN2RENRAB9A | |
| SCHEMBL3466476 | 0.89 | REN (0.35) | ALDH1A1KMT2ASMN1; SMN2RENLMNA | |
| SCHEMBL8257866 | 0.89 | REN (0.35) | ALDH1A1KMT2ASMN1; SMN2RENLMNA | |
| SCHEMBL4583132 | 0.89 | REN (0.35) | ALDH1A1KMT2ASMN1; SMN2RENLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1863803-B1 | SUBSTITUTED PIPERIDINES | NOVARTIS AG (CH) | 2010-09-01 | — | — | EP | disclosed |