Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC40A1 | Q9NP59 | 13/20 | 0.72 |
| ▸ | GAA | P10253 | 1/20 | 0.62 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | ATM | Q13315 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | NFKBIA | P25963 | 1/20 | 0.59 |
| ▸ | RELA | Q04206 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30854811 | 1.00 | SLC40A1 (0.72) | SLC40A1GAAGLO1MEN1KMT2A | |
| SCHEMBL11973660 | 0.86 | SLC40A1 (0.73) | SLC40A1MEN1KMT2ATDP1NFKBIA | |
| SCHEMBL30854809 | 0.86 | SLC40A1 (0.76) | SLC40A1GAAGLO1MEN1KMT2A | |
| SCHEMBL1507919 | 0.86 | SLC40A1 (0.76) | SLC40A1GAAGLO1MEN1KMT2A | |
| SCHEMBL30854823 | 0.85 | SLC40A1 (0.70) | SLC40A1GAAMEN1KMT2AATM | |
| SCHEMBL29255663 | 0.85 | SLC40A1 (0.70) | SLC40A1GAAMEN1KMT2AATM | |
| SCHEMBL11973684 | 0.84 | SLC40A1 (1.00) | SLC40A1GLO1MEN1KMT2ATDP1 | |
| SCHEMBL11972974 | 0.82 | SLC40A1 (1.00) | SLC40A1GLO1ATMTDP1NFKBIA | |
| SCHEMBL22315265 | 0.82 | ATM (0.74) | SLC40A1GAAGLO1MEN1KMT2A | |
| SCHEMBL30854819 | 0.82 | CXCR2 (0.77) | SLC40A1MEN1KMT2ATDP1NFKBIA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117865886-B | N- (quinoline-8-yl) quinoline-8-sulfonamide compound and application thereof | 中国药科大学 | 2024-05-10 | — | — | CN | disclosed |
| CN-117865886-A | N- (quinoline-8-yl) quinoline-8-sulfonamide compound and application thereof | 中国药科大学 | 2024-04-12 | — | — | CN | disclosed |