Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 5/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | XDH | P47989 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28765816 | 0.77 | ALDH1A1 (0.63) | HTTALDH1A1LMNAALOX15TSHR | |
| SCHEMBL3570507 | 0.75 | CHRNB2 (0.47) | HTTALDH1A1LMNAALOX15HSD17B10 | |
| SCHEMBL29256255 | 0.75 | POLB (0.72) | HTTALDH1A1LMNAALOX15TSHR | |
| SCHEMBL753087 | 0.74 | ALDH1A1 (0.60) | HTTALDH1A1LMNAALOX15TSHR | |
| SCHEMBL29978912 | 0.74 | ALDH1A1 (0.60) | HTTALDH1A1LMNAALOX15TSHR | |
| SCHEMBL3328395 | 0.72 | ALDH1A1 (0.58) | HTTALDH1A1LMNAALOX15TSHR | |
| SCHEMBL31751225 | 0.72 | ALOX5 (0.49) | ALDH1A1LMNAALOX15HSD17B10SMN1; SMN2 | |
| SCHEMBL8056884 | 0.72 | ALDH1A1 (0.42) | HTTALDH1A1LMNAALOX15HSD17B10 | |
| SCHEMBL8362944 | 0.71 | CHRNB2 (0.46) | HTTALDH1A1LMNAALOX15HSD17B10 | |
| SCHEMBL21905597 | 0.71 | HTT (0.63) | HTTALDH1A1LMNAALOX15TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4384267-A1 | SMALL MOLECULE STING ANTAGONISTS | Curadev Pharma Pvt. Ltd. (IN) | 2024-06-19 | — | — | EP | disclosed |
| CN-118159535-A | Small molecule STING antagonists | 库拉德夫制药私人有限公司 | 2024-06-07 | — | — | CN | disclosed |
| WO-2023017451-A1 | SMALL MOLECULE STING ANTAGONISTS | CURADEV PHARMA PVT. LTD. (IN) | 2023-02-16 | — | — | WO | disclosed |