SCHEMBL2925673

SCHEMBL2925673

FC(F)(F)c1ccc(NNc2ccccc2)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.59
TSHR P16473 1/20 0.59
CTSD P07339 1/20 0.57
TDP1 Q9NUW8 1/20 0.57
KIF11 P52732 2/20 0.56
NPC1 O15118 1/20 0.55
RAB9A P51151 1/20 0.55
EPHX2 P34913 1/20 0.48
KCNH3 Q9ULD8 1/20 0.47
MEN1 O00255 2/20 0.47
GAA P10253 2/20 0.47
MAPT P10636 2/20 0.47
KMT2A Q03164 2/20 0.47
KDM4E B2RXH2 1/20 0.47
GFER P55789 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
TRPV6 Q9H1D0 1/20 0.47
SMN1; SMN2 Q16637 2/20 0.46
CA1 P00915 1/20 0.45
CA2 P00918 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL503225 0.86 ALDH1A1 (0.62) ALDH1A1TSHRTDP1KIF11NPC1
Fluoride SCHEMBL8754786 0.84 ALDH1A1 (0.59) ALDH1A1TSHRTDP1KIF11NPC1
Hydrochloric Acid SCHEMBL2846563 0.84 ALDH1A1 (0.59) ALDH1A1TSHRTDP1KIF11NPC1
SCHEMBL4093215 0.83 MAPT (0.51) ALDH1A1TDP1KIF11RAB9AMEN1
SCHEMBL19648596 0.79 KIF11 (0.64) KIF11EPHX2CA1CA2PTGS1
SCHEMBL7267375 0.78 KIF11 (0.50) ALDH1A1TSHRKIF11NPC1RAB9A
Diphenylamine SCHEMBL31175856 0.78 ALDH1A1 (0.70) ALDH1A1TSHRTDP1KIF11NPC1
SCHEMBL17956747 0.77 KMT2A (0.69) ALDH1A1KIF11NPC1RAB9AEPHX2
SCHEMBL27214948 0.77 RAB9A (0.61) ALDH1A1TSHRKIF11NPC1RAB9A
SCHEMBL4548071 0.77 EPHX2 (0.85) TSHRNPC1RAB9AEPHX2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113024385-B Preparation method of 2,2 '-bis (trifluoromethyl) -4, 4' -diaminobiphenyl 西安瑞联新材料股份有限公司 2022-08-16 CN claimed
CN-113024385-A Preparation method of 2,2 '-bis (trifluoromethyl) -4, 4' -diaminobiphenyl 西安瑞联新材料股份有限公司 2021-06-25 CN claimed
CN-119118921-A Method for preparing diphenyl hydrazine or 2H-indazole compound by utilizing azobenzene compound 汕头大学 2024-12-13 CN disclosed
CN-116102453-B Method for preparing diphenyl hydrazine or 2H-indazole compound by utilizing azobenzene compound 汕头大学 2024-11-01 CN disclosed
CN-118026884-A Synthesis method of hydroazobenzene and hydroazobenzene 温州大学新材料与产业技术研究院 2024-05-14 CN disclosed
CN-115124430-B Synthesis process of 2,2' -di (trifluoromethyl) diaminobiphenyl 苏利制药科技江阴有限公司 2024-05-07 CN disclosed
CN-116102453-A Method for preparing diphenyl hydrazine or 2H-indazole compound by utilizing azobenzene compound 汕头大学 2023-05-12 CN disclosed
CN-112939796-B Synthetic method of 2,2 '-bis (trifluoromethyl) -4,4' -diaminobiphenyl 大连新阳光材料科技有限公司 2022-08-30 CN disclosed
CN-113024385-B Preparation method of 2,2 '-bis (trifluoromethyl) -4, 4' -diaminobiphenyl 西安瑞联新材料股份有限公司 2022-08-16 CN disclosed
CN-113024385-B Preparation method of 2,2 '-bis (trifluoromethyl) -4, 4' -diaminobiphenyl 西安瑞联新材料股份有限公司 2022-08-16 CN disclosed
CN-114867712-A Process for producing diaminobiphenyl compound 精化株式会社 2022-08-05 CN disclosed
CN-113024385-A Preparation method of 2,2 '-bis (trifluoromethyl) -4, 4' -diaminobiphenyl 西安瑞联新材料股份有限公司 2021-06-25 CN disclosed
CN-113024385-A Preparation method of 2,2 '-bis (trifluoromethyl) -4, 4' -diaminobiphenyl 西安瑞联新材料股份有限公司 2021-06-25 CN disclosed
CN-112939796-A Synthetic method of 2,2 '-bis (trifluoromethyl) -4,4' -diaminobiphenyl 大连新阳光材料科技有限公司 2021-06-11 CN disclosed
CN-105503925-B A kind of activation method of double (pinacol conjunction) diboranes and its application 南京大学 2017-07-28 CN disclosed
CN-105503925-A Activation method of bis(pinacolato)diborane and application thereof NANJING UNIVERSITY OF TECHNOLOGY 2016-04-20 CN disclosed
US-7772436-B2 Process for producing 2,2′-bis(trifluoromethyl)-4,4′-diaminobiphenyl AIR WATER INC. (JP) 2010-08-10 US disclosed
EP-1816118-B1 PROCESS FOR PRODUCING 2,2'-BIS(TRIFLUOROMETHYL)-4,4'-DIAMINOBIPHENYL AIR WATER INC (JP) 2010-01-27 EP disclosed
US-20090069602-A1 Process for Producing 2,2'-Bis(Trifluoromethyl)-4,4'-Diaminobiphenyl AIR WATER INC. (JP) 2009-03-12 US disclosed
EP-1816118-A1 PROCESS FOR PRODUCING 2,2'-BIS(TRIFLUOROMETHYL)-4,4'-DIAMINOBIPHENYL Air Water Inc. (JP) 2007-08-08 EP disclosed