Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | NAMPT | P43490 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.46 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.44 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.43 |
| ▸ | PRKCG | P05129 | 1/20 | 0.43 |
| ▸ | PRKACA | P17612 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29258188 | 0.87 | KMT2A (0.67) | HPGDALDH1A1LMNAKMT2AHTT | |
| SCHEMBL29258211 | 0.87 | SMN1; SMN2 (0.54) | KDM4ELMNAMAPTKMT2AROCK2 | |
| SCHEMBL29258199 | 0.87 | NAMPT (0.53) | HPGDALDH1A1NAMPTLMNAKMT2A | |
| SCHEMBL29258215 | 0.86 | HDAC1 (0.58) | HPGDALDH1A1KDM4ELMNAMAPT | |
| SCHEMBL29258571 | 0.84 | AKR1C3 (0.60) | HPGDKDM4EKMT2AHTTROCK2 | |
| SCHEMBL29258321 | 0.83 | AKR1C3 (0.50) | HPGDALDH1A1KDM4EMAPTKMT2A | |
| SCHEMBL30780061 | 0.82 | HPGD (0.77) | HPGDALDH1A1NAMPTCA2KDM4E | |
| SCHEMBL1568387 | 0.82 | HPGD (0.77) | HPGDALDH1A1NAMPTCA2KDM4E | |
| SCHEMBL29258255 | 0.81 | MMP13 (0.52) | NAMPTKDM4ELMNAHTTROCK2 | |
| SCHEMBL29258227 | 0.81 | MMP13 (0.65) | CA2LMNAHTTROCK2MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118108664-A | NAMPT agonist and preparation method and application thereof | 中国人民解放军海军军医大学 | 2024-05-31 | — | — | CN | claimed |
| CN-118108664-A | NAMPT agonist and preparation method and application thereof | 中国人民解放军海军军医大学 | 2024-05-31 | — | — | CN | disclosed |