Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | ROCK2 | O75116 | 5/20 | 0.49 |
| ▸ | ROCK1 | Q13464 | 4/20 | 0.49 |
| ▸ | PRKACA | P17612 | 2/20 | 0.49 |
| ▸ | GSK3A | P49840 | 2/20 | 0.49 |
| ▸ | GSK3B | P49841 | 2/20 | 0.49 |
| ▸ | PRKX | P51817 | 2/20 | 0.49 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.49 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.49 |
| ▸ | PRKCG | P05129 | 1/20 | 0.49 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29258571 | 0.89 | AKR1C3 (0.60) | AKR1C3MEN1KMT2AROCK2ROCK1 | |
| SCHEMBL29258510 | 0.88 | SENP1 (0.55) | AKR1C3RAB9AROCK2ROCK1PRKACA | |
| SCHEMBL29258544 | 0.88 | NPC1 (0.57) | RAB9AMEN1KMT2AROCK2ROCK1 | |
| SCHEMBL29258530 | 0.88 | ROCK2 (0.51) | ROCK2ROCK1PRKACAGSK3AGSK3B | |
| SCHEMBL29258094 | 0.88 | ROCK2 (0.64) | ROCK2ROCK1PRKACAGSK3AGSK3B | |
| SCHEMBL29258129 | 0.84 | AKR1C3 (0.49) | AKR1C3KMT2AROCK2ROCK1PRKACA | |
| SCHEMBL29258229 | 0.84 | HDAC1 (0.50) | AKR1C3ROCK2ROCK1PRKACAGSK3A | |
| SCHEMBL29258169 | 0.84 | SMN1; SMN2 (0.47) | AKR1C3ROCK2ROCK1PRKACAGSK3A | |
| SCHEMBL29258227 | 0.84 | MMP13 (0.65) | AKR1C3RAB9AROCK2ROCK1PRKACA | |
| SCHEMBL29258255 | 0.84 | MMP13 (0.52) | AKR1C3ROCK2ROCK1PRKACAGSK3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118108664-A | NAMPT agonist and preparation method and application thereof | 中国人民解放军海军军医大学 | 2024-05-31 | — | — | CN | claimed |
| CN-118108664-A | NAMPT agonist and preparation method and application thereof | 中国人民解放军海军军医大学 | 2024-05-31 | — | — | CN | disclosed |