Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.53 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 5/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.48 |
| ▸ | PRKCA | P17252 | 1/20 | 0.48 |
| ▸ | GRK2 | P25098 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.47 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29258159 | 0.86 | HPGD (0.62) | HTTMAPTROCK2ROCK1HPGD | |
| SCHEMBL29258188 | 0.84 | KMT2A (0.67) | HDAC1HTTROCK2ROCK1HPGD | |
| SCHEMBL29258199 | 0.84 | NAMPT (0.53) | HDAC1HTTROCK2ROCK1HPGD | |
| SCHEMBL29258211 | 0.84 | SMN1; SMN2 (0.54) | MAPTROCK2KDM4EPRKCAGRK2 | |
| SCHEMBL29258612 | 0.83 | NPC1 (0.57) | HDAC1HTTROCK2ROCK1GAA | |
| SCHEMBL1568381 | 0.83 | HDAC1 (0.72) | HDAC1HTTMAPTROCK2ROCK1 | |
| SCHEMBL29258236 | 0.82 | HDAC3 (0.49) | HDAC1HTTROCK2ROCK1HPGD | |
| SCHEMBL29258094 | 0.81 | ROCK2 (0.64) | ROCK2ROCK1HPGDALDH1A1KDM4E | |
| SCHEMBL29258310 | 0.80 | HDAC3 (0.49) | HDAC1HTTROCK2HPGDPOLB | |
| SCHEMBL6848785 | 0.80 | HTT (0.83) | HDAC1HTTMAPTHPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118108664-A | NAMPT agonist and preparation method and application thereof | 中国人民解放军海军军医大学 | 2024-05-31 | — | — | CN | claimed |
| CN-118108664-A | NAMPT agonist and preparation method and application thereof | 中国人民解放军海军军医大学 | 2024-05-31 | — | — | CN | disclosed |