Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 7/20 | 0.57 |
| ▸ | MAOB | P27338 | 1/20 | 0.57 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.54 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | KDM1A | O60341 | 2/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29258164 | 1.00 | NAMPT (0.57) | NAMPTMAOBHDAC1HDAC3HDAC2 | |
| SCHEMBL29258248 | 0.90 | MLYCD (0.57) | NAMPTMAOBLMNAMAPTCA12 | |
| SCHEMBL29258252 | 0.90 | MLYCD (0.57) | NAMPTMAOBLMNAMAPTCA12 | |
| SCHEMBL29258128 | 0.89 | NAMPT (0.64) | NAMPTHDAC1HDAC3HDAC2NCOR2 | |
| SCHEMBL29258125 | 0.89 | NAMPT (0.64) | NAMPTHDAC1HDAC3HDAC2NCOR2 | |
| SCHEMBL29258630 | 0.83 | EPHX2 (0.59) | NAMPTMAOBEPHX2 | |
| SCHEMBL29258633 | 0.83 | EPHX2 (0.59) | NAMPTMAOBEPHX2 | |
| SCHEMBL29258285 | 0.82 | NAMPT (0.85) | NAMPT | |
| SCHEMBL29258099 | 0.81 | ROCK2 (0.68) | NAMPT | |
| SCHEMBL29258096 | 0.81 | ROCK2 (0.68) | NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118108664-A | NAMPT agonist and preparation method and application thereof | 中国人民解放军海军军医大学 | 2024-05-31 | — | — | CN | claimed |
| CN-118108664-A | NAMPT agonist and preparation method and application thereof | 中国人民解放军海军军医大学 | 2024-05-31 | — | — | CN | disclosed |