Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLYCD | O95822 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | NAMPT | P43490 | 5/20 | 0.53 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.53 |
| ▸ | SENP1 | Q9P0U3 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.51 |
| ▸ | SENP2 | Q9HC62 | 1/20 | 0.51 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29258248 | 1.00 | MLYCD (0.57) | MLYCDL3MBTL1NAMPTMAPK14SENP1 | |
| SCHEMBL29258167 | 0.90 | NAMPT (0.57) | L3MBTL1NAMPTMAOBLMNAMAPT | |
| SCHEMBL29258164 | 0.90 | NAMPT (0.57) | L3MBTL1NAMPTMAOBLMNAMAPT | |
| SCHEMBL29258096 | 0.86 | ROCK2 (0.68) | NAMPTMAPK14SENP1CYP3A4CYP2D6 | |
| SCHEMBL29258099 | 0.86 | ROCK2 (0.68) | NAMPTMAPK14SENP1CYP3A4CYP2D6 | |
| SCHEMBL29258796 | 0.83 | NAMPT (0.69) | L3MBTL1NAMPTHTTTHRBMEN1 | |
| SCHEMBL29258281 | 0.83 | NAMPT (0.72) | MLYCDNAMPT | |
| SCHEMBL1568282 | 0.82 | MLYCD (0.74) | MLYCDL3MBTL1NAMPTMAPK14MEN1 | |
| SCHEMBL29258633 | 0.80 | EPHX2 (0.59) | NAMPTMAOBCYP3A4CYP2D6CYP2C19 | |
| SCHEMBL29258630 | 0.80 | EPHX2 (0.59) | NAMPTMAOBCYP3A4CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118108664-A | NAMPT agonist and preparation method and application thereof | 中国人民解放军海军军医大学 | 2024-05-31 | — | — | CN | claimed |
| CN-118108664-A | NAMPT agonist and preparation method and application thereof | 中国人民解放军海军军医大学 | 2024-05-31 | — | — | CN | disclosed |