Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.55 |
| ▸ | APP | P05067 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | MMP13 | P45452 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.50 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.50 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.49 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29258094 | 0.89 | ROCK2 (0.64) | APPCYP3A4LMNAMMP13ROCK2 | |
| SCHEMBL29258571 | 0.88 | AKR1C3 (0.60) | HDAC1CYP3A4MAPK14HTTMMP13 | |
| SCHEMBL29258255 | 0.87 | MMP13 (0.52) | HDAC1CYP3A4MAPK14LMNAHTT | |
| SCHEMBL29258227 | 0.87 | MMP13 (0.65) | NPC1RAB9AHDAC1CYP3A4MAPK14 | |
| SCHEMBL29258289 | 0.86 | L3MBTL1 (0.63) | HDAC1CYP3A4MAPK14LMNAHTT | |
| SCHEMBL29258637 | 0.86 | AKR1C3 (0.54) | HDAC1CYP3A4MAPK14LMNAHTT | |
| SCHEMBL29258277 | 0.86 | SMN1; SMN2 (0.57) | HDAC1CYP3A4MAPK14LMNAHTT | |
| SCHEMBL29258215 | 0.83 | HDAC1 (0.58) | HDAC1LMNAHTTGAAROCK2 | |
| SCHEMBL29258321 | 0.82 | AKR1C3 (0.50) | NPC1RAB9ACYP3A4MMP13AKR1C3 | |
| SCHEMBL29258169 | 0.81 | SMN1; SMN2 (0.47) | NPC1HDAC1CYP3A4MAPK14LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118108664-A | NAMPT agonist and preparation method and application thereof | 中国人民解放军海军军医大学 | 2024-05-31 | — | — | CN | claimed |
| CN-118108664-A | NAMPT agonist and preparation method and application thereof | 中国人民解放军海军军医大学 | 2024-05-31 | — | — | CN | disclosed |