Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 4/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29258460 | 0.91 | ALDH1A1 (0.38) | ALDH1A1L3MBTL1KMT2ARXFP1HTT | |
| SCHEMBL29258806 | 0.88 | SIGMAR1 (0.39) | ALDH1A1L3MBTL1KMT2ARXFP1IRAK4 | |
| SCHEMBL29258780 | 0.86 | ALDH1A1 (0.38) | ALDH1A1L3MBTL1KMT2ASMN1; SMN2IRAK4 | |
| SCHEMBL29258406 | 0.86 | L3MBTL1 (0.40) | ALDH1A1L3MBTL1KMT2ASMN1; SMN2CYP2C19 | |
| SCHEMBL29258517 | 0.85 | L3MBTL1 (0.41) | ALDH1A1L3MBTL1KMT2ASMN1; SMN2CYP2C19 | |
| SCHEMBL16985296 | 0.84 | IRAK4 (0.41) | ALDH1A1L3MBTL1KMT2ARXFP1HTT | |
| SCHEMBL29258602 | 0.82 | ALDH1A1 (0.34) | ALDH1A1L3MBTL1KMT2ARXFP1 | |
| SCHEMBL29258453 | 0.81 | ALDH1A1 (0.34) | ALDH1A1L3MBTL1KMT2ARXFP1MAPT | |
| SCHEMBL29258363 | 0.80 | IRAK4 (0.38) | ALDH1A1L3MBTL1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL22648384 | 0.80 | ALDH1A1 (0.40) | ALDH1A1L3MBTL1KMT2AHPGDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118108708-A | Aminopyrimidine derivative with antifungal activity and application thereof | 中国人民解放军海军军医大学 | 2024-05-31 | — | — | CN | disclosed |