SCHEMBL29258602

SCHEMBL29258602

CCC(C)N1CCC(n2cc([N+](=O)[O-])cn2)C(F)C1

nearest known ligand 0.34

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
KMT2A Q03164 1/20 0.30
RXFP1 Q9HBX9 1/20 0.30
HRH3 Q9Y5N1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29258453 0.89 ALDH1A1 (0.34) ALDH1A1L3MBTL1KMT2ARXFP1HRH3
SCHEMBL29258376 0.82 ALDH1A1 (0.37) ALDH1A1L3MBTL1KMT2ARXFP1
SCHEMBL16985296 0.80 IRAK4 (0.41) ALDH1A1L3MBTL1KMT2ARXFP1
SCHEMBL29258460 0.80 ALDH1A1 (0.38) ALDH1A1L3MBTL1KMT2ARXFP1
SCHEMBL29258806 0.77 SIGMAR1 (0.39) ALDH1A1L3MBTL1KMT2ARXFP1
SCHEMBL29258363 0.76 IRAK4 (0.38) ALDH1A1L3MBTL1KMT2A
SCHEMBL29258393 0.76 L3MBTL1 (0.39) ALDH1A1L3MBTL1KMT2A
SCHEMBL29258780 0.76 ALDH1A1 (0.38) ALDH1A1L3MBTL1KMT2A
SCHEMBL29258406 0.76 L3MBTL1 (0.40) ALDH1A1L3MBTL1KMT2A
SCHEMBL29258384 0.75 L3MBTL1 (0.39) ALDH1A1L3MBTL1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118108708-A Aminopyrimidine derivative with antifungal activity and application thereof 中国人民解放军海军军医大学 2024-05-31 CN disclosed