Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SENP1 | Q9P0U3 | 4/20 | 0.55 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.49 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.48 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.48 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.48 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.48 |
| ▸ | PRKCG | P05129 | 1/20 | 0.48 |
| ▸ | PRKACA | P17612 | 1/20 | 0.48 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | AKT1 | P31749 | 1/20 | 0.48 |
| ▸ | GSK3A | P49840 | 1/20 | 0.48 |
| ▸ | GSK3B | P49841 | 1/20 | 0.48 |
| ▸ | PRKX | P51817 | 1/20 | 0.48 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.48 |
| ▸ | PRKG2 | Q13237 | 1/20 | 0.48 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.48 |
| ▸ | PRKG1 | Q13976 | 1/20 | 0.48 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.48 |
| ▸ | CDC42BPA | Q5VT25 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29258810 | 0.92 | AKR1C3 (0.53) | SENP1AKR1C3ROCK2ROCK1RPS6KA5 | |
| SCHEMBL29258321 | 0.88 | AKR1C3 (0.50) | SENP1AKR1C3ROCK2ROCK1RPS6KA5 | |
| SCHEMBL29258637 | 0.88 | AKR1C3 (0.54) | SENP1AKR1C3ROCK2ROCK1RPS6KA5 | |
| SCHEMBL29258544 | 0.88 | NPC1 (0.57) | SENP1ROCK2ROCK1RPS6KA5MAP4K4 | |
| SCHEMBL29258129 | 0.88 | AKR1C3 (0.49) | SENP1AKR1C3ROCK2ROCK1RPS6KA5 | |
| SCHEMBL29258530 | 0.88 | ROCK2 (0.51) | SENP1ROCK2ROCK1RPS6KA5MAP4K4 | |
| SCHEMBL29258169 | 0.85 | SMN1; SMN2 (0.47) | AKR1C3ROCK2ROCK1RPS6KA5MAP4K4 | |
| SCHEMBL29258250 | 0.84 | KMT2A (0.53) | SENP1AKR1C3ROCK2ROCK1RPS6KA5 | |
| SCHEMBL29258184 | 0.84 | KMT2A (0.53) | SENP1AKR1C3ROCK2ROCK1RPS6KA5 | |
| SCHEMBL29258390 | 0.84 | KMT2A (0.51) | SENP1AKR1C3ROCK2ROCK1RPS6KA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118108664-A | NAMPT agonist and preparation method and application thereof | 中国人民解放军海军军医大学 | 2024-05-31 | — | — | CN | claimed |
| CN-118108664-A | NAMPT agonist and preparation method and application thereof | 中国人民解放军海军军医大学 | 2024-05-31 | — | — | CN | disclosed |