Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 7/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.50 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.50 |
| ▸ | AURKA | O14965 | 1/20 | 0.50 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.48 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.48 |
| ▸ | GSK3B | P49841 | 2/20 | 0.48 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.48 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.48 |
| ▸ | PRKCG | P05129 | 1/20 | 0.48 |
| ▸ | PRKACA | P17612 | 1/20 | 0.48 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | AKT1 | P31749 | 1/20 | 0.48 |
| ▸ | GSK3A | P49840 | 1/20 | 0.48 |
| ▸ | PRKX | P51817 | 1/20 | 0.48 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.48 |
| ▸ | PRKG2 | Q13237 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29258693 | 0.92 | AURKA (0.57) | ROCK2HDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL29258321 | 0.88 | AKR1C3 (0.50) | ROCK2HDAC2ROCK1MAP4K4GSK3B | |
| SCHEMBL29258289 | 0.88 | L3MBTL1 (0.63) | ROCK2HDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL29258229 | 0.88 | HDAC1 (0.50) | ROCK2HDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL29258510 | 0.88 | SENP1 (0.55) | ROCK2HDAC3HDAC1HDAC2ROCK1 | |
| SCHEMBL29258544 | 0.88 | NPC1 (0.57) | ROCK2ROCK1MAP4K4GSK3BCLK4 | |
| SCHEMBL29258094 | 0.85 | ROCK2 (0.64) | ROCK2AURKAROCK1GSK3BCLK4 | |
| SCHEMBL29258236 | 0.84 | HDAC3 (0.49) | ROCK2HDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL29258310 | 0.84 | HDAC3 (0.49) | ROCK2HDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL29258309 | 0.84 | HTT (0.45) | ROCK2HDAC3HDAC1HDAC2NCOR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118108664-A | NAMPT agonist and preparation method and application thereof | 中国人民解放军海军军医大学 | 2024-05-31 | — | — | CN | claimed |
| CN-118108664-A | NAMPT agonist and preparation method and application thereof | 中国人民解放军海军军医大学 | 2024-05-31 | — | — | CN | disclosed |