Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 3/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.47 |
| ▸ | MMP13 | P45452 | 2/20 | 0.47 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.47 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.47 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.47 |
| ▸ | PRKCG | P05129 | 1/20 | 0.47 |
| ▸ | PRKACA | P17612 | 1/20 | 0.47 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29258510 | 0.92 | SENP1 (0.55) | AKR1C3HDAC2HDAC6HDAC1HDAC8 | |
| SCHEMBL29258637 | 0.90 | AKR1C3 (0.54) | AKR1C3HDAC2HDAC6HDAC1HDAC8 | |
| SCHEMBL29258169 | 0.89 | SMN1; SMN2 (0.47) | AKR1C3HDAC2HDAC6HDAC1HDAC8 | |
| SCHEMBL29258129 | 0.87 | AKR1C3 (0.49) | AKR1C3HDAC2HDAC6HDAC1HDAC8 | |
| SCHEMBL29258693 | 0.87 | AURKA (0.57) | AKR1C3HDAC2HDAC6HDAC1HDAC8 | |
| SCHEMBL29258255 | 0.84 | MMP13 (0.52) | AKR1C3HDAC2HDAC6HDAC1HDAC8 | |
| SCHEMBL29258227 | 0.84 | MMP13 (0.65) | AKR1C3HDAC2HDAC6HDAC1HDAC8 | |
| SCHEMBL29258184 | 0.84 | KMT2A (0.53) | AKR1C3HDAC2HDAC6HDAC1HDAC8 | |
| SCHEMBL29258321 | 0.84 | AKR1C3 (0.50) | AKR1C3HDAC2HDAC6HDAC8MMP13 | |
| SCHEMBL29258571 | 0.83 | AKR1C3 (0.60) | AKR1C3HDAC2HDAC6HDAC1HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118108664-A | NAMPT agonist and preparation method and application thereof | 中国人民解放军海军军医大学 | 2024-05-31 | — | — | CN | claimed |
| CN-118108664-A | NAMPT agonist and preparation method and application thereof | 中国人民解放军海军军医大学 | 2024-05-31 | — | — | CN | disclosed |