Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | APAF1 | O14727 | 1/20 | 0.54 |
| ▸ | MITF | O75030 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | CDC25B | P30305 | 4/20 | 0.52 |
| ▸ | CDC25A | P30304 | 3/20 | 0.52 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | S100A4 | P26447 | 1/20 | 0.48 |
| ▸ | TRAP1 | Q12931 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | F13A1 | P00488 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21940525 | 1.00 | MAPT (0.54) | MAPTL3MBTL1ALDH1A1LMNAKDM4E | |
| SCHEMBL9709635 | 1.00 | MAPT (0.54) | MAPTL3MBTL1ALDH1A1LMNAKDM4E | |
| SCHEMBL30201802 | 1.00 | MAPT (0.54) | MAPTL3MBTL1ALDH1A1LMNAKDM4E | |
| SCHEMBL11421782 | 0.98 | MAPT (0.55) | MAPTL3MBTL1ALDH1A1LMNAKDM4E | |
| SCHEMBL30005823 | 0.94 | MAPT (0.56) | MAPTL3MBTL1ALDH1A1LMNAKDM4E | |
| SCHEMBL4446630 | 0.94 | MAPT (0.56) | MAPTL3MBTL1ALDH1A1LMNAKDM4E | |
| SCHEMBL13649357 | 0.87 | MAPT (0.59) | MAPTL3MBTL1ALDH1A1LMNAKDM4E | |
| SCHEMBL25753957 | 0.85 | KDM4E (0.46) | MAPTL3MBTL1ALDH1A1LMNAKDM4E | |
| SCHEMBL11411263 | 0.84 | MAPT (0.49) | MAPTL3MBTL1ALDH1A1LMNAKDM4E | |
| SCHEMBL21878889 | 0.83 | MAPT (0.59) | MAPTL3MBTL1ALDH1A1LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240400536-A1 | IDEBENONE DERIVATIVES AND THEIR USE IN TREATING PLANTS | MITORX THERAPEUTICS LTD (GB) | 2024-12-05 | — | — | US | disclosed |
| CN-118234716-A | Idebenone derivatives and their use in the treatment of plants | 米托克斯治疗有限公司 | 2024-06-21 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240400536-A1 | IDEBENONE DERIVATIVES AND THEIR USE IN TREATING PLANTS | AIFM1, TUFM, SQOR | MAPT 2216/4885L3MBTL1 4152/4885ALDH1A1 1104/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.