Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 3/20 | 0.47 |
| ▸ | SCN9A | Q15858 | 5/20 | 0.45 |
| ▸ | CA1 | P00915 | 6/20 | 0.39 |
| ▸ | CA2 | P00918 | 6/20 | 0.39 |
| ▸ | CA9 | Q16790 | 5/20 | 0.38 |
| ▸ | CA12 | O43570 | 3/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | HTR1D | P28221 | 1/20 | 0.38 |
| ▸ | HTR1B | P28222 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HTR1E | P28566 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | HTR5A | P47898 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 2/20 | 0.36 |
| ▸ | CA7 | P43166 | 2/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29264198 | 0.87 | CA2 (0.42) | HTR7SCN9ACA1CA2CA9 | |
| SCHEMBL29264216 | 0.86 | CSNK2A2 (0.42) | HTR7SCN9ACA1CA2HTR1A | |
| SCHEMBL29264203 | 0.86 | HTR7 (0.40) | HTR7SCN9ACA1CA2CA9 | |
| SCHEMBL29264247 | 0.86 | HTR7 (0.48) | HTR7CA1CA2CA9CA12 | |
| SCHEMBL29264212 | 0.84 | SCN9A (0.41) | HTR7SCN9ACA1CA2PTGES2 | |
| SCHEMBL29264253 | 0.84 | HTR7 (0.64) | HTR7SCN9ACA1CA2CA9 | |
| SCHEMBL29264240 | 0.83 | SCN9A (0.48) | HTR7SCN9ACA1CA2PTGES2 | |
| SCHEMBL27200641 | 0.82 | HTR7 (0.38) | HTR7SCN9ACA1CA2HTR1A | |
| SCHEMBL29264168 | 0.81 | HTR7 (0.39) | HTR7SCN9ACA1CA2HTR1A | |
| SCHEMBL27200642 | 0.81 | LTA4H (0.48) | SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118206476-A | Alkylamine substituted sulfonamide compound and application thereof | 上海璃道医药科技有限公司 | 2024-06-18 | — | — | CN | disclosed |