Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 3/20 | 0.43 |
| ▸ | CNR2 | P34972 | 3/20 | 0.43 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | FPR2 | P25090 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29264358 | 0.96 | EPHX1 (0.46) | EPHX1HPGDKDM4EPKMCNR1 | |
| SCHEMBL7581179 | 0.96 | EPHX1 (0.46) | EPHX1HPGDKDM4EPKMCNR1 | |
| SCHEMBL7853362 | 0.80 | LMNA (0.46) | KDM4ECNR1CNR2FKBP1ASMN1; SMN2 | |
| SCHEMBL29264336 | 0.79 | LTA4H (0.43) | KDM4ECNR1CNR2FKBP1ASMN1; SMN2 | |
| SCHEMBL29264338 | 0.79 | LTA4H (0.43) | KDM4ECNR1CNR2FKBP1ASMN1; SMN2 | |
| SCHEMBL31040357 | 0.79 | EPHX1 (0.51) | EPHX1HPGDCNR1CNR2FKBP1A | |
| SCHEMBL4387757 | 0.78 | HPGD (0.49) | EPHX1HPGDKDM4EPKMRECQL | |
| SCHEMBL4093887 | 0.77 | HPGD (0.57) | EPHX1HPGDKDM4EPKMRECQL | |
| SCHEMBL15212209 | 0.77 | CNR1 (0.43) | KDM4ECNR1CNR2FKBP1AALDH1A1 | |
| SCHEMBL29264319 | 0.77 | FKBP1A (0.42) | KDM4ECNR1CNR2FKBP1AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020082420-A1 | Bicyclic heterocycles, pharmaceutical compositions containing them, their use, and processes for preparing them | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-06-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020082420-A1 | Bicyclic heterocycles, pharmaceutical compositions containing them, their use, and processes for preparing them | PKD1, REN, CYP11B1 | EPHX1 2458/4885HPGD 173/4885KDM4E 4527/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.