Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | AR | P10275 | 1/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29264864 | 0.92 | NPSR1 (0.47) | NPSR1MAPK1SMN1; SMN2KMT2AKDM4E | |
| SCHEMBL29264882 | 0.89 | KDM4E (0.47) | SMN1; SMN2KMT2AKDM4EMAPTTSHR | |
| SCHEMBL29264847 | 0.88 | KDM4E (0.50) | SMN1; SMN2KMT2AKDM4EMAPTTSHR | |
| SCHEMBL29264850 | 0.87 | KDM4E (0.52) | SMN1; SMN2KMT2AKDM4EMAPTTSHR | |
| SCHEMBL29264853 | 0.84 | KDM4E (0.47) | MAPK1SMN1; SMN2KMT2AKDM4EMAPT | |
| SCHEMBL29264868 | 0.83 | MAPK8 (0.50) | NPSR1SMN1; SMN2KMT2AKDM4EMAPT | |
| SCHEMBL29264884 | 0.81 | MAPK8 (0.50) | MAPK1SMN1; SMN2KMT2AKDM4ETSHR | |
| SCHEMBL29264855 | 0.81 | KMT2A (0.46) | NPSR1MAPK1SMN1; SMN2KMT2AKDM4E | |
| SCHEMBL29264858 | 0.80 | SLC6A3 (0.50) | NPSR1MAPK1SMN1; SMN2KMT2AKDM4E | |
| SCHEMBL29264863 | 0.80 | SLC6A4 (0.45) | KMT2AKDM4EMAPTSLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116854631-B | 4-Aryl-2-pyridone compound and preparation method thereof | 安徽中医药大学 | 2025-04-15 | — | — | CN | disclosed |
| CN-116854631-A | 4-aryl-2-pyridone compound and preparation method thereof | 安徽中医药大学 | 2023-10-10 | — | — | CN | disclosed |