Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.51 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.40 |
| ▸ | WNT3A | P56704 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.40 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | KDM4A | O75164 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30975213 | 1.00 | ALDH1A1 (0.53) | ALDH1A1MAPTL3MBTL1P2RX7FAAH | |
| SCHEMBL14543576 | 0.81 | FAAH (0.48) | ALDH1A1P2RX7FAAHTP53HPGD | |
| SCHEMBL5160509 | 0.80 | P2RX7 (0.50) | ALDH1A1MAPTL3MBTL1P2RX7FAAH | |
| SCHEMBL30931068 | 0.79 | P2RX7 (0.52) | ALDH1A1MAPTP2RX7FAAHCTNNB1 | |
| SCHEMBL2021292 | 0.79 | P2RX7 (0.52) | ALDH1A1MAPTP2RX7FAAHCTNNB1 | |
| Hydrochloric Acid SCHEMBL30402677 | 0.78 | P2RX7 (0.50) | ALDH1A1MAPTP2RX7FAAHCTNNB1 | |
| Hydrochloric Acid SCHEMBL28987505 | 0.78 | P2RX7 (0.50) | ALDH1A1MAPTP2RX7FAAHCTNNB1 | |
| SCHEMBL14200259 | 0.78 | P2RX7 (0.41) | ALDH1A1MAPTL3MBTL1P2RX7FAAH | |
| SCHEMBL27895302 | 0.77 | P2RX7 (0.50) | ALDH1A1MAPTL3MBTL1P2RX7FAAH | |
| SCHEMBL6480081 | 0.77 | ALDH1A1 (0.59) | ALDH1A1MAPTL3MBTL1SMN1; SMN2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118239953-A | Compounds for the treatment of PI3K gamma mediated diseases and uses thereof | 中国科学院合肥物质科学研究院 | 2024-06-25 | — | — | CN | disclosed |