SCHEMBL29266809

SCHEMBL29266809

Oc1cccc2nc3c4ccc(Br)nc4c4nc(Br)ccc4c3nc12

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 2/20 0.62
ALDH1A1 P00352 2/20 0.61
RAB9A P51151 2/20 0.61
KMT2A Q03164 2/20 0.61
GAA P10253 1/20 0.61
MAPT P10636 1/20 0.61
NPSR1 Q6W5P4 1/20 0.61
NQO2 P16083 6/20 0.49
CYP1A2 P05177 2/20 0.47
MYC P01106 1/20 0.42
MAX P61244 1/20 0.42
GUSB P08236 2/20 0.38
ESR1 P03372 1/20 0.37
ESR2 Q92731 1/20 0.37
METAP2 P50579 2/20 0.35
MMP2 P08253 1/20 0.35
CHRM1 P11229 1/20 0.35
TSHR P16473 1/20 0.35
COMT P21964 1/20 0.35
ADRA1A P35348 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30618508 1.00 ACHE (0.62) ACHEALDH1A1RAB9AKMT2AGAA
SCHEMBL762952 0.82 ACHE (0.72) ACHEALDH1A1RAB9AKMT2AGAA
SCHEMBL13872598 0.80 ACHE (0.58) ACHEALDH1A1RAB9AKMT2AGAA
SCHEMBL3181469 0.79 ACHE (1.00) ACHEALDH1A1RAB9AKMT2AGAA
SCHEMBL345562 0.77 ALDH1A1 (1.00) ACHEALDH1A1RAB9AKMT2AGAA
SCHEMBL13439504 0.77 ACHE (0.85) ACHEALDH1A1RAB9AKMT2AGAA
SCHEMBL23612578 0.76 ACHE (0.75) ACHEALDH1A1RAB9AKMT2AGAA
SCHEMBL20475303 0.75 ALDH1A1 (0.95) ACHEALDH1A1RAB9AKMT2AGAA
SCHEMBL6065573 0.74 METAP2 (0.59) ACHEALDH1A1RAB9AKMT2AGAA
SCHEMBL18387365 0.73 ACHE (0.69) ACHEALDH1A1RAB9AKMT2AGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114044781-B Thermal activation delayed red light material with coumarin phenanthroline pyrazine as parent nucleus and application of thermal activation delayed red light material in organic electroluminescent device 吉林大学 2023-10-17 CN disclosed