Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 5/20 | 0.38 |
| ▸ | HPGDS | O60760 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NTRK1 | P04629 | 3/20 | 0.34 |
| ▸ | GPR183 | P32249 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.32 |
| ▸ | NNMT | P40261 | 1/20 | 0.31 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.31 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.31 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.31 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30996264 | 0.77 | ALDH1A1 (0.40) | ERN1KDM4EALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL2871260 | 0.75 | NNMT (0.45) | HPGDSKDM4EPOLBSMN1; SMN2L3MBTL1 | |
| SCHEMBL29267430 | 0.71 | ERN1 (0.39) | ERN1HPGDSKDM4ESMN1; SMN2L3MBTL1 | |
| SCHEMBL29267452 | 0.68 | ALDH1A1 (0.44) | ERN1ALDH1A1POLBSMN1; SMN2HTT | |
| SCHEMBL30540236 | 0.67 | ALOX5AP (0.43) | ERN1KDM4EALDH1A1 | |
| SCHEMBL26635226 | 0.67 | ALOX5AP (0.43) | ERN1KDM4EALDH1A1 | |
| SCHEMBL26635316 | 0.67 | NOTUM (0.45) | ERN1KDM4EALDH1A1L3MBTL1HTT | |
| SCHEMBL17979362 | 0.66 | TRPA1 (0.34) | KDM4EALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL31490671 | 0.65 | ALOX5AP (0.37) | ERN1KDM4EPOLBCCNE2CCNE1 | |
| SCHEMBL26635271 | 0.64 | ERN1 (0.36) | ERN1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118324761-A | USP inhibitor, preparation method and application thereof | 北京华森英诺生物科技有限公司 | 2024-07-12 | — | — | CN | disclosed |