Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 5/20 | 0.36 |
| ▸ | RAB9A | P51151 | 5/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ERN1 | O75460 | 4/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ACLY | P53396 | 1/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | STAT3 | P40763 | 1/20 | 0.31 |
| ▸ | STAT1 | P42224 | 1/20 | 0.31 |
| ▸ | CASP3 | P42574 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26635161 | 0.78 | XDH (0.46) | ALDH1A1MAPTERN1TDP1ACLY | |
| SCHEMBL30540244 | 0.78 | XDH (0.46) | ALDH1A1MAPTERN1TDP1ACLY | |
| SCHEMBL29267455 | 0.77 | ERN1 (0.38) | ALDH1A1SMN1; SMN2KDM4EPOLBRAB9A | |
| SCHEMBL17979362 | 0.76 | TRPA1 (0.34) | ALDH1A1SMN1; SMN2KDM4EPOLBTDP1 | |
| SCHEMBL30540238 | 0.74 | ALOX5AP (0.36) | ALDH1A1SMN1; SMN2KDM4EPOLBERN1 | |
| SCHEMBL26635203 | 0.74 | ALOX5AP (0.36) | ALDH1A1SMN1; SMN2KDM4EPOLBERN1 | |
| SCHEMBL30996252 | 0.73 | JUN (0.31) | — | |
| SCHEMBL29267452 | 0.71 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2POLBNPC1RAB9A | |
| SCHEMBL156478 | 0.70 | HTT (0.39) | ALDH1A1HTTHSD17B10TDP1PDK2 | |
| SCHEMBL16635035 | 0.70 | TRPA1 (0.34) | ALDH1A1SMN1; SMN2KDM4EPOLBACLY |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118324761-A | USP inhibitor, preparation method and application thereof | 北京华森英诺生物科技有限公司 | 2024-07-12 | — | — | CN | disclosed |