Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.62 |
| ▸ | HTR3B | O95264 | 1/20 | 0.62 |
| ▸ | HTR3A | P46098 | 1/20 | 0.62 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.62 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | ESR1 | P03372 | 1/20 | 0.53 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2926794 | 1.00 | HTR3E (0.62) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL30452241 | 1.00 | HTR3E (0.62) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL5982772 | 0.94 | HTR3E (0.56) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL5981549 | 0.94 | HTR3E (0.56) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL15188838 | 0.87 | HTR3E (0.55) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL8141886 | 0.87 | ESR1 (0.64) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL8141891 | 0.87 | ESR1 (0.64) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL13737803 | 0.87 | HTR3E (0.50) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL2167283 | 0.86 | HTR3E (0.62) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL8134495 | 0.85 | HTR3E (0.53) | HTR3EHTR3BHTR3AHTR3DHTR3C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220402858-A1 | METHOD FOR PREPARING DIAMINOBIPHENYL COMPOUND | SEIKA CORPORATION (JP) | 2022-12-22 | — | — | US | disclosed |
| US-20220402858-A1 | METHOD FOR PREPARING DIAMINOBIPHENYL COMPOUND | SEIKA CORPORATION (JP) | 2022-12-22 | — | — | US | disclosed |
| CN-113831259-A | Synthetic method of aromatic azo compound | 内蒙古工业大学 | 2021-12-24 | — | — | CN | disclosed |
| CN-109704987-B | Method for synthesizing 2-fluorobenzene amine compound | 浙江工业大学 | 2021-10-15 | — | — | CN | disclosed |
| WO-2021131549-A1 | METHOD FOR PRODUCING DIAMINOBIPHENYL COMPOUND | セイカ株式会社 | 2021-07-01 | — | — | WO | disclosed |
| EP-2231185-A1 | METHODS AND COMPOSITIONS FOR TREATING LIQUID TUMORS | Elan Pharmaceuticals Inc. (US) | 2010-09-29 | — | — | EP | disclosed |
| WO-2010108108-A2 | POLYAMINE DERIVATIVES | EGEN, INC. (US) | 2010-09-23 | — | — | WO | disclosed |
| US-7772436-B2 | Process for producing 2,2′-bis(trifluoromethyl)-4,4′-diaminobiphenyl | AIR WATER INC. (JP) | 2010-08-10 | — | — | US | disclosed |
| EP-1816118-B1 | PROCESS FOR PRODUCING 2,2'-BIS(TRIFLUOROMETHYL)-4,4'-DIAMINOBIPHENYL | AIR WATER INC (JP) | 2010-01-27 | — | — | EP | disclosed |
| WO-2009075806-A1 | METHODS AND COMPOSITIONS FOR TREATING LIQUID TUMORS | ELAN PHARMACEUTICALS, INC. (US) | 2009-06-18 | — | — | WO | disclosed |
| US-20090069602-A1 | Process for Producing 2,2'-Bis(Trifluoromethyl)-4,4'-Diaminobiphenyl | AIR WATER INC. (JP) | 2009-03-12 | — | — | US | disclosed |
| EP-1816118-A1 | PROCESS FOR PRODUCING 2,2'-BIS(TRIFLUOROMETHYL)-4,4'-DIAMINOBIPHENYL | Air Water Inc. (JP) | 2007-08-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220402858-A1 | METHOD FOR PREPARING DIAMINOBIPHENYL COMPOUND | TERT, NT5C, DDC | HTR3E 3782/4885HTR3B 2670/4885HTR3A 3805/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.