Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | REN | P00797 | 8/20 | 0.35 |
| ▸ | AMPD2 | Q01433 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23123105 | 0.76 | KDM4E (0.37) | MEN1KMT2AKDM4EPOLBGAA | |
| SCHEMBL22054795 | 0.72 | TMEM97 (0.45) | OPRM1SIGMAR1MEN1KMT2AREN | |
| SCHEMBL16719986 | 0.69 | RECQL (0.55) | KMT2AKDM4EPOLBGAATRPA1 | |
| SCHEMBL291695 | 0.69 | REN (0.45) | REN | |
| SCHEMBL293228 | 0.68 | REN (0.44) | MEN1KMT2ARENPOLBALDH1A1 | |
| SCHEMBL7555132 | 0.65 | DDB1 (0.45) | MEN1KMT2AKDM4EPOLBGAA | |
| SCHEMBL23123776 | 0.65 | ALDH1A1 (0.44) | MEN1KMT2AKDM4EPOLBALDH1A1 | |
| SCHEMBL23122239 | 0.65 | NOS1 (0.40) | MEN1KMT2AKDM4EALDH1A1TSHR | |
| SCHEMBL14811854 | 0.64 | GAA (0.44) | MEN1KMT2AGAAALDH1A1MAPT | |
| SCHEMBL29004244 | 0.63 | GAA (0.42) | MEN1KMT2AKDM4EPOLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2036896-B1 | CYCLIC AMINE COMPOUND | DAIICHI SANKYO CO LTD (JP) | 2012-03-14 | — | — | EP | disclosed |
| EP-2036896-A1 | CYCLIC AMINE COMPOUND | Daiichi Sankyo Company, Limited (JP) | 2009-03-18 | — | — | EP | disclosed |