Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAAT5 | Q96KN8 | 10/20 | 0.59 |
| ▸ | PLAAT4 | Q9UL19 | 10/20 | 0.59 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.55 |
| ▸ | PLAAT3 | P53816 | 9/20 | 0.54 |
| ▸ | PLAAT2 | Q9NWW9 | 9/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4279627 | 0.89 | KEAP1 (0.73) | PLAAT5PLAAT4KEAP1ALDH1A1FFAR1 | |
| SCHEMBL5566614 | 0.81 | HDAC1 (0.69) | PLAAT5PLAAT4KEAP1ALDH1A1FFAR1 | |
| SCHEMBL11141595 | 0.81 | KEAP1 (0.61) | PLAAT5PLAAT4KEAP1ALDH1A1FFAR1 | |
| SCHEMBL1371070 | 0.81 | KEAP1 (0.61) | PLAAT5PLAAT4KEAP1ALDH1A1FFAR1 | |
| SCHEMBL6629478 | 0.81 | CES2 (0.74) | PLAAT5PLAAT4KEAP1ALDH1A1FFAR1 | |
| SCHEMBL258545 | 0.80 | KEAP1 (0.67) | PLAAT5PLAAT4KEAP1ALDH1A1FFAR1 | |
| SCHEMBL29078123 | 0.80 | KEAP1 (0.67) | PLAAT5PLAAT4KEAP1ALDH1A1FFAR1 | |
| SCHEMBL12950241 | 0.79 | ALDH1A1 (0.61) | PLAAT5PLAAT4KEAP1ALDH1A1FFAR1 | |
| SCHEMBL3514632 | 0.79 | ALDH1A1 (0.61) | PLAAT5PLAAT4KEAP1ALDH1A1FFAR1 | |
| SCHEMBL4646048 | 0.78 | CES1 (0.77) | ALDH1A1HDAC8HDAC6TDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116964202-A | Interfering RNA targeting severe acute respiratory syndrome related coronaviruses and use thereof for the treatment of covd-19 | 中天(上海)生物科技有限公司 | 2023-10-27 | — | — | CN | disclosed |