Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP14 | Q460N5 | 20/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29270705 | 0.93 | PARP14 (0.39) | PARP14 | |
| SCHEMBL29270729 | 0.82 | PARP14 (0.38) | PARP14 | |
| SCHEMBL29270722 | 0.79 | CHRM2 (0.38) | — | |
| SCHEMBL29270744 | 0.76 | TP53 (0.34) | — | |
| SCHEMBL29270773 | 0.76 | EGLN2 (0.34) | — | |
| SCHEMBL29270781 | 0.76 | TP53 (0.37) | — | |
| SCHEMBL29270692 | 0.75 | AGTR1 (0.36) | — | |
| SCHEMBL29270690 | 0.74 | ALDH1A1 (0.41) | — | |
| SCHEMBL29270771 | 0.73 | XIAP (0.34) | — | |
| SCHEMBL29270810 | 0.73 | TP53 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116964048-A | Bicyclic tetrahydroazepine derivatives for the treatment of cancer | 豪夫迈·罗氏有限公司 | 2023-10-27 | — | — | CN | disclosed |