Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | ASPH | Q12797 | 2/20 | 0.45 |
| ▸ | KDM8 | Q8N371 | 2/20 | 0.45 |
| ▸ | RIOX2 | Q8IUF8 | 1/20 | 0.45 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.39 |
| ▸ | P4HTM | Q9NXG6 | 6/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.38 |
| ▸ | GABRP | O00591 | 1/20 | 0.38 |
| ▸ | GABRD | O14764 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11894710 | 0.80 | KMO (0.46) | KDM4EASPHKDM8RIOX2P4HTM | |
| SCHEMBL29272155 | 0.79 | KDM4E (0.41) | KDM4EASPHKDM8P4HTMALDH1A1 | |
| SCHEMBL31032278 | 0.79 | KDM4E (0.41) | KDM4EASPHKDM8P4HTMALDH1A1 | |
| SCHEMBL30546833 | 0.76 | KDM4E (0.49) | KDM4EASPHKDM8RIOX2P4HTM | |
| SCHEMBL15350397 | 0.75 | KDM4E (0.40) | KDM4EASPHKDM8P4HTMALDH1A1 | |
| SCHEMBL30546859 | 0.74 | EGLN2 (0.37) | SMN1; SMN2GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL7083217 | 0.70 | KDM4E (0.50) | KDM4EASPHKDM8P4HTMALDH1A1 | |
| SCHEMBL9853727 | 0.69 | ESR2 (0.44) | SRD5A2LMNAKMT2A | |
| SCHEMBL21078911 | 0.69 | KDM4E (0.37) | KDM4EASPHKDM8P4HTMALDH1A1 | |
| SCHEMBL21078949 | 0.69 | MAPT (0.42) | KDM4EASPHKDM8P4HTMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116670131-A | PHD inhibitor compounds, compositions, and methods of use | 阿克比治疗有限公司 | 2023-08-29 | — | — | CN | disclosed |