SCHEMBL29273139

SCHEMBL29273139

O=C1C=CC(=O)C(c2cccc3cc4ccccc4cc23)=C1c1cccc2cc3ccccc3cc12

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES1 P23141 3/20 0.43
MAOA P21397 3/20 0.43
IDO1 P14902 2/20 0.43
MAOB P27338 2/20 0.43
CDC25B P30305 1/20 0.43
AKT1 P31749 1/20 0.43
SNCA P37840 1/20 0.43
MAP2K1 Q02750 1/20 0.43
PIN1 Q13526 1/20 0.43
EHMT2 Q96KQ7 1/20 0.43
NSD1 Q96L73 1/20 0.43
EHMT1 Q9H9B1 1/20 0.43
NQO1 P15559 1/20 0.42
ALDH1A1 P00352 10/20 0.42
KDM4E B2RXH2 5/20 0.42
GAA P10253 3/20 0.42
HPGD P15428 5/20 0.40
MEN1 O00255 5/20 0.40
KMT2A Q03164 5/20 0.40
MAPK1 P28482 4/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4594745 0.82 ALDH1A1 (0.52) CES1MAOAIDO1MAOBCDC25B
SCHEMBL2975246 0.79 MAOA (0.46) CES1MAOAIDO1MAOBCDC25B
SCHEMBL29354014 0.79 ALDH1A1 (0.50) CES1MAOANQO1ALDH1A1KDM4E
SCHEMBL2871930 0.79 ALDH1A1 (0.50) CES1MAOANQO1ALDH1A1KDM4E
SCHEMBL6851988 0.78 ALDH1A1 (0.62) CES1MAOAIDO1MAOBCDC25B
SCHEMBL28075400 0.78 MAOA (0.44) CES1MAOAIDO1MAOBCDC25B
Methane SCHEMBL27586778 0.78 MAOA (0.44) CES1MAOAIDO1MAOBCDC25B
SCHEMBL797427 0.78 MAOA (0.44) CES1MAOAIDO1MAOBCDC25B
Hydrochloric Acid SCHEMBL28173381 0.78 MAOA (0.44) CES1MAOAIDO1MAOBCDC25B
SCHEMBL27749022 0.78 MAOA (0.44) CES1MAOAIDO1MAOBCDC25B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118325078-A Preparation method and application of benzoquinone conjugated polymer 中国科学院宁波材料技术与工程研究所 2024-07-12 CN claimed