Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 7/20 | 0.52 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.52 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.51 |
| ▸ | GCK | P35557 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | MMP8 | P22894 | 1/20 | 0.46 |
| ▸ | MMP14 | P50281 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7793618 | 0.83 | P4HTM (0.47) | P4HTMGCKMEN1KMT2ARAB9A | |
| SCHEMBL20377232 | 0.81 | FDPS (0.60) | FDPSCA9MMP2MMP8MMP14 | |
| SCHEMBL7793628 | 0.77 | FDPS (0.60) | FDPSFDFT1CA9MMP2MMP8 | |
| SCHEMBL20377227 | 0.75 | FDPS (0.51) | FDPSFDFT1 | |
| SCHEMBL15163963 | 0.75 | FDPS (0.62) | FDPSFDFT1CA9MMP2MMP8 | |
| SCHEMBL6243281 | 0.74 | PPARG (0.51) | FDPSFDFT1 | |
| SCHEMBL1552689 | 0.74 | P4HTM (0.54) | P4HTMGCKCA9RAB9ACA12 | |
| SCHEMBL19023188 | 0.74 | P4HTM (0.54) | P4HTMGCKRAB9ALMNACYP1A2 | |
| SCHEMBL7784742 | 0.74 | FDPS (0.68) | FDPSFDFT1CA9MMP2CA12 | |
| SCHEMBL6239582 | 0.73 | FDPS (0.50) | FDPSFDFT1MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0762883-B1 | PYRIDYLBISPHOSPHONATES FOR USE AS A THERAPEUTICAL AGENT | LEIRAS OY (FI) | 2001-11-14 | — | — | EP | claimed |