SCHEMBL29274133

SCHEMBL29274133

CCCN(C=O)c1ccccc1Nc1ccccn1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
MAPK10 P53779 1/20 0.50
GFER P55789 1/20 0.50
TLR4 O00206 1/20 0.40
TLR2 O60603 1/20 0.40
CYP2C19 P33261 1/20 0.39
GRM5 P41594 1/20 0.39
CA12 O43570 1/20 0.39
CA1 P00915 1/20 0.39
CA9 Q16790 1/20 0.39
HTT P42858 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
TSHR P16473 1/20 0.36
ATM Q13315 1/20 0.36
KCNA5 P22460 1/20 0.36
KCNH2 Q12809 1/20 0.36
NPC1 O15118 1/20 0.36
RAB9A P51151 1/20 0.36
GAA P10253 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30761103 0.85 MEN1 (0.42) MEN1KMT2AMAPK10GFERTLR4
SCHEMBL30761104 0.83 PDE10A (0.40) MEN1KMT2AMAPK10SMN1; SMN2NPC1
SCHEMBL29274138 0.80 MEN1 (0.56) MEN1KMT2AMAPK10GFERTLR4
SCHEMBL29274130 0.79 MAPT (0.38) MEN1KMT2ACYP2C19CA12CA1
SCHEMBL29274137 0.76 ALDH1A1 (0.33) CA12CA9SMN1; SMN2ATMRAB9A
SCHEMBL7985486 0.72 MAPK10 (0.61) MEN1KMT2AMAPK10GFERCYP2C19
SCHEMBL29274141 0.72 LPAR1 (0.35) KMT2ASMN1; SMN2
SCHEMBL7985498 0.71 MEN1 (0.66) MEN1KMT2AMAPK10GFERGRM5
SCHEMBL28337704 0.71 CYP2D6 (0.47) CYP2C19SMN1; SMN2TSHRKCNA5KCNH2
SCHEMBL3279571 0.70 MEN1 (1.00) MEN1KMT2AMAPK10GFERGRM5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117069747-A Method for synthesizing N-heterocyclic carbene complex by utilizing hydrolysate of imidazole salt 石河子大学 2023-11-17 CN claimed
CN-117105934-A Method for preparing benzodiazepine compound by selective hydrogenation 石河子大学 2023-11-24 CN disclosed
CN-117069747-A Method for synthesizing N-heterocyclic carbene complex by utilizing hydrolysate of imidazole salt 石河子大学 2023-11-17 CN disclosed