Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.66 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.66 |
| ▸ | GFER | P55789 | 1/20 | 0.66 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.48 |
| ▸ | GRM5 | P41594 | 1/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7985486 | 0.86 | MAPK10 (0.61) | MEN1KMT2AMAPK10GFERGRM5 | |
| SCHEMBL3279571 | 0.80 | MEN1 (1.00) | MEN1KMT2AMAPK10GFERGRM5 | |
| SCHEMBL11443309 | 0.80 | MEN1 (0.58) | MEN1KMT2AMAPK10GFERPTGS1 | |
| SCHEMBL1548694 | 0.78 | ALDH1A1 (0.54) | MEN1KMT2APTGS1GAARAB9A | |
| SCHEMBL6952759 | 0.78 | NPSR1 (0.67) | MEN1KMT2AGAANPC1RAB9A | |
| SCHEMBL5393403 | 0.76 | MAPK14 (0.50) | MEN1KMT2APTK2MAPK14PTGS1 | |
| SCHEMBL2583677 | 0.76 | MEN1 (0.51) | MEN1KMT2AMAPK10GFERGAA | |
| SCHEMBL31220877 | 0.76 | MAPK10 (0.73) | MEN1KMT2AMAPK10GFERPTK2 | |
| SCHEMBL7941542 | 0.76 | MAPK10 (0.73) | MEN1KMT2AMAPK10GFERPTK2 | |
| SCHEMBL3265735 | 0.76 | MEN1 (0.80) | MEN1KMT2AMAPK10GFERGRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235730-B1 | ANTICHOLESTEROL AGENT, ANTILIPEMIC AGENT | JAPAN TOBACCO, INC. (JP) | 2001-05-22 | — | — | US | disclosed |
| EP-0970954-A1 | 3-PIPERIDYL-4-OXOQUINAZOLINE DERIVATIVES AND MEDICINCAL COMPOSITIONS CONTAINING THE SAME | JAPAN TOBACCO INC. (JP) | 2000-01-12 | — | — | EP | disclosed |