Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK10 | P53779 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | GFER | P55789 | 1/20 | 0.61 |
| ▸ | GRM5 | P41594 | 2/20 | 0.49 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7985498 | 0.86 | MEN1 (0.66) | MAPK10MEN1KMT2AGFERGRM5 | |
| SCHEMBL3960441 | 0.83 | GRM5 (0.68) | MAPK10MEN1KMT2AGFERGRM5 | |
| SCHEMBL13813554 | 0.80 | ADRA2B (0.46) | MEN1KMT2AGRM5ADRA2BADRA2C | |
| SCHEMBL3279571 | 0.78 | MEN1 (1.00) | MAPK10MEN1KMT2AGFERGRM5 | |
| SCHEMBL2583677 | 0.76 | MEN1 (0.51) | MAPK10MEN1KMT2AGFERALDH1A1 | |
| SCHEMBL11443309 | 0.74 | MEN1 (0.58) | MAPK10MEN1KMT2AGFERCYP1A2 | |
| SCHEMBL7982172 | 0.73 | MAPT (0.47) | MEN1KMT2AADRA2BADRA2CALDH1A1 | |
| SCHEMBL31220877 | 0.73 | MAPK10 (0.73) | MAPK10MEN1KMT2AGFERADRA2B | |
| SCHEMBL7941542 | 0.73 | MAPK10 (0.73) | MAPK10MEN1KMT2AGFERADRA2B | |
| SCHEMBL3265735 | 0.73 | MEN1 (0.80) | MAPK10MEN1KMT2AGFERGRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235730-B1 | ANTICHOLESTEROL AGENT, ANTILIPEMIC AGENT | JAPAN TOBACCO, INC. (JP) | 2001-05-22 | — | — | US | disclosed |
| EP-0970954-A1 | 3-PIPERIDYL-4-OXOQUINAZOLINE DERIVATIVES AND MEDICINCAL COMPOSITIONS CONTAINING THE SAME | JAPAN TOBACCO INC. (JP) | 2000-01-12 | — | — | EP | disclosed |