Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | GSK3B | P49841 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.46 |
| ▸ | ERN1 | O75460 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9018924 | 0.84 | ALDH1A1 (0.50) | POLBMAOBSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL29274289 | 0.84 | POLB (0.55) | HTTMAPTPOLBSMN1; SMN2KMT2A | |
| SCHEMBL25666676 | 0.80 | SMN1; SMN2 (0.59) | HTTMAPTGSK3BMAOBSMN1; SMN2 | |
| SCHEMBL8992964 | 0.79 | MAPT (0.56) | MAPTKMT2AMEN1NPC1RAB9A | |
| Bicarbonate SCHEMBL27706334 | 0.79 | ALDH1A1 (0.55) | PTPN1SMN1; SMN2KMT2AMEN1NPC1 | |
| SCHEMBL9689325 | 0.78 | MAPT (0.63) | HTTMAPTPOLBSMN1; SMN2KMT2A | |
| SCHEMBL4071946 | 0.78 | MAPT (0.60) | MAPTPOLBSMN1; SMN2KMT2ARAB9A | |
| SCHEMBL70372 | 0.78 | TSHR (0.57) | MAPTPOLBRAB9AALDH1A1LMNA | |
| SCHEMBL1773407 | 0.78 | LOXL2 (0.53) | MAPTSMN1; SMN2KMT2AMEN1NPC1 | |
| SCHEMBL2579068 | 0.78 | KEAP1 (0.56) | MAPTRAB9AALDH1A1LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118239888-A | Modularized synthesis method and application of acridine compound | 厦门大学 | 2024-06-25 | — | — | CN | disclosed |