Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Malonic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Malonic Acid SCHEMBL29456949 | 0.96 | CA4 (1.00) | — | |
| Malonic Acid SCHEMBL107285 | 0.96 | — | — | |
| Malonic Acid SCHEMBL15464 | 0.96 | — | — | |
| Malonic Acid SCHEMBL28314403 | 0.92 | — | — | |
| Malonic Acid SCHEMBL28854452 | 0.92 | CA4 (0.92) | — | |
| Malonic Acid SCHEMBL28253669 | 0.92 | CA4 (0.92) | — | |
| Malonic Acid SCHEMBL28315716 | 0.92 | — | — | |
| Malonic Acid SCHEMBL106339 | 0.92 | — | — | |
| Malonic Acid SCHEMBL11307221 | 0.92 | CA4 (0.92) | — | |
| Malonic Acid SCHEMBL10594878 | 0.92 | CA4 (0.92) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4072522-B1 | MALONATE SALT FOR USE IN THE TREATMENT OR PREVENTION OF ISCHAEMIC STROKE REPERFUSION INJURY | CAMBRIDGE ENTPR LTD (GB) | 2026-01-28 | — | — | EP | disclosed |
| WO-2025125766-A1 | TREATMENT OR PREVENTION OF ISCHAEMIA REPERFUSION INJURY | CAMBRIDGE ENTERPRISE LIMITED (GB) | 2025-06-19 | — | — | WO | disclosed |
| US-20240252457-A1 | Treatment or Prevention of Ischaemia Reperfusion Injury | CAMBRIDGE ENTERPRISE LIMITED (GB) | 2024-08-01 | — | — | US | disclosed |
| EP-4355315-A1 | TREATMENT OR PREVENTION OF ISCHAEMIA REPERFUSION INJURY | Cambridge Enterprise Limited (GB) | 2024-04-24 | — | — | EP | disclosed |
| US-20220409562-A1 | Treatment or Prevention of Ischaemic Stroke Reperfusion Injury | CAMBRIDGE ENTERPRISE LIMITED (GB) | 2022-12-29 | — | — | US | disclosed |
| WO-2022263792-A1 | TREATMENT OR PREVENTION OF ISCHAEMIA REPERFUSION INJURY | CAMBRIDGE ENTERPRISE LIMITED (GB) | 2022-12-22 | — | — | WO | disclosed |
| EP-4072522-A1 | TREATMENT OR PREVENTION OF ISCHAEMIC STROKE REPERFUSION INJURY | Cambridge Enterprise Limited (GB) | 2022-10-19 | — | — | EP | disclosed |
| CN-110172019-B | Metal salts of malonic acid as nucleating additives for crystalline thermoplastics | 印度石油有限公司 | 2022-03-04 | — | — | CN | disclosed |
| WO-2021116670-A1 | TREATMENT OR PREVENTION OF ISCHAEMIC STROKE REPERFUSION INJURY | CAMBRIDGE ENTERPRISE LIMITED (GB) | 2021-06-17 | — | — | WO | disclosed |
| EP-1892242-B1 | Method of purifying 3-phenyl-3,4-epoxy-2-butanol derivatives by liquid-liquid extraction | SUMITOMO CHEMICAL CO (JP) | 2010-09-29 | — | — | EP | disclosed |
| US-7459573-B2 | Method of purifying epoxy compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2008-12-02 | — | — | US | disclosed |
| US-20080081921-A1 | Method of purifying epoxy compound | SUMITOMO CHEMICAL COMPANY, LIMITED | 2008-04-03 | — | — | US | disclosed |
| EP-1892242-A1 | Method of purifying 3-phenyl-3,4-epoxy-2-butanol derivatives by liquid-liquid extraction | Sumitomo Chemical Company, Limited (JP) | 2008-02-27 | — | — | EP | disclosed |