Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 3/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | ERN1 | O75460 | 1/20 | 0.42 |
| ▸ | IAPP | P10997 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 3/20 | 0.38 |
| ▸ | CA2 | P00918 | 3/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 6/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 5/20 | 0.36 |
| ▸ | GAA | P10253 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | THRB | P10828 | 3/20 | 0.35 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.35 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | RECQL | P46063 | 3/20 | 0.35 |
| ▸ | MPI | P34949 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5992999 | 0.98 | TRPA1 (0.48) | TRPA1ATMERN1IAPPCA1 | |
| SCHEMBL9618491 | 0.78 | ERN1 (0.61) | TRPA1ERN1IAPPCA1CA2 | |
| SCHEMBL276965 | 0.78 | TRIM24 (0.52) | TRPA1ERN1CA1CA2NFKB1 | |
| SCHEMBL31000832 | 0.78 | TRIM24 (0.52) | TRPA1ERN1CA1CA2NFKB1 | |
| SCHEMBL7113862 | 0.77 | ERN1 (0.43) | TRPA1ATMERN1IAPPCA1 | |
| SCHEMBL16956018 | 0.76 | TRPA1 (0.52) | TRPA1ATMERN1IAPPCA1 | |
| SCHEMBL24832683 | 0.75 | ERN1 (0.44) | TRPA1ERN1GAAALDH1A1NPC1 | |
| SCHEMBL2359891 | 0.75 | ERN1 (0.42) | TRPA1ATMERN1IAPPCA1 | |
| SCHEMBL5440903 | 0.75 | ERN1 (0.44) | TRPA1ERN1IAPPCA1CA2 | |
| SCHEMBL210332 | 0.74 | ERN1 (0.61) | TRPA1ATMERN1IAPPCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118344512-A | Mannich base and preparation method and application thereof | 中国石油化工股份有限公司 | 2024-07-16 | — | — | CN | disclosed |
| CN-118344511-A | Mannich base and preparation method and application thereof | 中国石油化工股份有限公司 | 2024-07-16 | — | — | CN | disclosed |