Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.55 |
| ▸ | HTT | P42858 | 6/20 | 0.55 |
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6851183 | 0.84 | ALDH1A1 (0.57) | POLBKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL1784763 | 0.84 | ALDH1A1 (0.64) | POLBKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL2189025 | 0.78 | ALDH1A1 (0.59) | POLBKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL2187571 | 0.78 | ALDH1A1 (0.63) | POLBKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL30512327 | 0.78 | ALDH1A1 (0.62) | POLBKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL379309 | 0.78 | ALDH1A1 (0.62) | POLBKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL27608925 | 0.78 | ALDH1A1 (0.63) | POLBKMT2AALDH1A1SMN1; SMN2HTT | |
| SCHEMBL3153751 | 0.77 | ALDH1A1 (0.69) | POLBKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL14519061 | 0.77 | ALDH1A1 (0.71) | POLBKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL323912 | 0.77 | KMT2A (0.59) | POLBKMT2AMEN1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117285511-A | Indole hybridized quinolone compound and preparation method and application thereof | 西南大学 | 2023-12-26 | — | — | CN | disclosed |